Literature summary extracted from

Mizugaki, M.; Nishimaki, T.; Shiraishi, T.; Kawaguchi, A.; Okuda, S.; Yamanaka, H.
Studies on the metabolism of unsaturated fatty acids. IX. Stereochemical studies of the reaction catalyzed by trans-2-enoyl-coenzyme A reductase of Escherichia coli (1982), J. Biochem., 92, 1649-1654.

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.3.1.38	Escherichia coli	-	K12	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
1.3.1.38	partial	Escherichia coli

Reaction

EC Number	Reaction	Comment	Organism	Reaction ID
1.3.1.38	acyl-CoA + NADP+ = trans-2,3-dehydroacyl-CoA + NADPH + H+	mechanism: anti addition of hydrogen via a 2Re, 3Re attack on trans double bond	Escherichia coli	a

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.3.1.38	trans-2-octenoyl-CoA + NADPH	-	Escherichia coli	octanoyl-CoA + NADP+	-	?

Temperature Optimum [°C]

EC Number	Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
1.3.1.38	25	-	assay at	Escherichia coli

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.3.1.38	NADPH	-	Escherichia coli

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Release 2023.1 (January 2023)