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Literature summary extracted from

  • Slack, C.R.; Grattan Roughan, P.; Browse, J.
    Evidence for an oleoyl phosphatidylcholine desaturase in microsomal preparations from cotyledons of safflower (Carthamus tinctorius) seed (1979), Biochem. J., 179, 649-656.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.19.22 sn-glycero-3-phosphocholine
-
 Carthamus tinctorius

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.19.22 microsome
-
 Carthamus tinctorius
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.19.22 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + ferrocytochrome b5 + O2 + H+ Carthamus tinctorius
-
 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine + ferricytochrome b5 + H2O
-
 ?
1.14.19.22 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + ferrocytochrome b5 + O2 + H+ Carthamus tinctorius cultivar 0-22
-
 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine + ferricytochrome b5 + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.19.22 Carthamus tinctorius
-
-
-
1.14.19.22 Carthamus tinctorius
-
 safflower
-
1.14.19.22 Carthamus tinctorius cultivar 0-22
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.19.22 cotyledon
-
 Carthamus tinctorius
-
1.14.19.22 seed
-
 Carthamus tinctorius
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.14.19.22 additional information
-
-
 Carthamus tinctorius

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.19.22 1,2-dioleoylphosphatidylcholine + 2 ferrocytochrome b5 + O2 + 2 H+ the rate of desaturation of endogenous oleoyl phosphatidylcholine is much greater that of exogenous dioleoyl phosphatidylcholine Carthamus tinctorius 1,2-linoleoylphosphatidylcholine + 2 ferricytochrome b5 + 2 H2O
-
 ?
1.14.19.22 1,2-dioleoylphosphatidylcholine + 2 ferrocytochrome b5 + O2 + 2 H+ the rate of desaturation of endogenous oleoyl phosphatidylcholine is much greater that of exogenous dioleoyl phosphatidylcholine Carthamus tinctorius cultivar 0-22 1,2-linoleoylphosphatidylcholine + 2 ferricytochrome b5 + 2 H2O
-
 ?
1.14.19.22 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + ferrocytochrome b5 + O2 + H+
-
 Carthamus tinctorius 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine + ferricytochrome b5 + H2O
-
 ?
1.14.19.22 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + ferrocytochrome b5 + O2 + H+
-
 Carthamus tinctorius cultivar 0-22 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine + ferricytochrome b5 + H2O
-
 ?
1.14.19.22 additional information esterification of oleate at position 1 and 2 Carthamus tinctorius ?
-
 ?
1.14.19.22 additional information esterification of oleate at position 1 and 2 Carthamus tinctorius cultivar 0-22 ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.19.22 oleoyl phosphatidylcholine desaturase ambiguous Carthamus tinctorius

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.19.22 NAD+
-
 Carthamus tinctorius