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Literature summary extracted from

  • Gamborg, O.L.; Keeley, F.W.
    Aromatic metabolism in plants I. A study of the prephenate dehydrogenase from bean plants (1966), Biochim. Biophys. Acta, 115, 65-72.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.3.1.13 4-chloromercuriphenylsulfonic acid
-
 Phaseolus vulgaris
1.3.1.13 N-ethylmaleimide
-
 Phaseolus vulgaris

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.3.1.13 0.077
-
 NADP+
-
 Phaseolus vulgaris
1.3.1.13 0.079
-
 NADP+
-
 Phaseolus vulgaris
1.3.1.13 0.13
-
 prephenate
-
 Phaseolus vulgaris
1.3.1.13 0.18
-
 prephenate
-
 Phaseolus vulgaris

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.1.13 prephenate + NADP+ Phaseolus vulgaris
-
 4-hydroxyphenylpyruvate + CO2 + NADPH
-
 ?
1.3.1.13 prephenate + NADP+ Vicia faba
-
 4-hydroxyphenylpyruvate + CO2 + NADPH
-
 ?
1.3.1.13 prephenate + NADP+ Klebsiella aerogenes
-
 4-hydroxyphenylpyruvate + CO2 + NADPH
-
 ?
1.3.1.13 prephenate + NADP+ Vigna radiata
-
 4-hydroxyphenylpyruvate + CO2 + NADPH
-
 ?
1.3.1.13 prephenate + NADP+ Phaseolus coccineus
-
 4-hydroxyphenylpyruvate + CO2 + NADPH
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.13 Klebsiella aerogenes
-
-
-
1.3.1.13 no activity in Beta vulgaris subsp. vulgaris
-
 red beet, Beta vulgaris ssp. var. conditiva, Beta vulgaris ssp. vulgaris var. rubra
-
1.3.1.13 no activity in Oryza sativa
-
 rice
-
1.3.1.13 no activity in Pisum sativum
-
 pea
-
1.3.1.13 no activity in Triticum aestivum
-
 wheat
-
1.3.1.13 Phaseolus coccineus
-
 scarlet runner bean, L.
-
1.3.1.13 Phaseolus vulgaris
-
 wax bean, L. var.Bountiful
-
1.3.1.13 Vicia faba
-
 broad bean, L. var. Windsor
-
1.3.1.13 Vigna radiata
-
 mung bean, [L.] Wilczek, originally classified as Phaseolus aureus [L.] Roxb.
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.3.1.13
-
 Phaseolus vulgaris

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.1.13 cotyledon
-
 Phaseolus vulgaris
-
1.3.1.13 cotyledon
-
 Vicia faba
-
1.3.1.13 cotyledon
-
 Vigna radiata
-
1.3.1.13 cotyledon
-
 Phaseolus coccineus
-
1.3.1.13 seedling
-
 Vigna radiata
-
1.3.1.13 shoot
-
 Vigna radiata
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.1.13 prephenate + NADP+
-
 Phaseolus vulgaris 4-hydroxyphenylpyruvate + CO2 + NADPH
-
 ?
1.3.1.13 prephenate + NADP+
-
 Vicia faba 4-hydroxyphenylpyruvate + CO2 + NADPH
-
 ?
1.3.1.13 prephenate + NADP+
-
 Klebsiella aerogenes 4-hydroxyphenylpyruvate + CO2 + NADPH
-
 ?
1.3.1.13 prephenate + NADP+
-
 Vigna radiata 4-hydroxyphenylpyruvate + CO2 + NADPH
-
 ?
1.3.1.13 prephenate + NADP+
-
 Phaseolus coccineus 4-hydroxyphenylpyruvate + CO2 + NADPH
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.3.1.13 7.5
-
-
 Phaseolus vulgaris
1.3.1.13 7.5
-
-
 Vigna radiata

pH Range

EC Number pH Minimum pH Maximum Comment Organism
1.3.1.13 4 10.8
-
 Phaseolus vulgaris

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
1.3.1.13 7 8 maximum stability in this range at 22°C Phaseolus vulgaris

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.1.13 NADP+ NAD+ is ineffective in replacing NADP+ Phaseolus vulgaris