Literature summary extracted from
Sampathkumar, P.; Morrison, J.F.
Chorismate mutase-prephenate dehydrogenase from Escherichia coli. Purification and properties of the bifunctional enzyme (1982), Biochim. Biophys. Acta, 702, 204-211.
Molecular Weight [Da]
EC Number |
Molecular Weight [Da] |
Molecular Weight Maximum [Da] |
Comment |
Organism |
---|
1.3.1.12 |
78000 |
100000 |
chorismate mutase-prephenate dehydrogenase bifunctional enzyme, gel electrophoresis |
Escherichia coli |
1.3.1.12 |
78000 |
100000 |
chorismate mutase-prephenate dehydrogenase bifunctional enzyme, sedimentation equilibrium centrifugation |
Escherichia coli |
Natural Substrates/ Products (Substrates)
EC Number |
Natural Substrates |
Organism |
Comment (Nat. Sub.) |
Natural Products |
Comment (Nat. Pro.) |
Rev. |
Reac. |
---|
1.3.1.12 |
prephenate + NAD+ |
Escherichia coli |
biosynthesis of L-tyrosine |
4-hydroxyphenylpyruvate + NADH + CO2 |
- |
? |
|
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
---|
1.3.1.12 |
Escherichia coli |
- |
- |
- |
Purification (Commentary)
EC Number |
Purification (Comment) |
Organism |
---|
1.3.1.12 |
chorismate mutase-prephenate dehydrogenase bifunctional enzyme |
Escherichia coli |
Storage Stability
EC Number |
Storage Stability |
Organism |
---|
1.3.1.12 |
-20°C, 0.1 M N-ethylmorpholine, pH 7.0, 21 mM citrate, 10% v/v glycerol, 1 mM EDTA, 1 mM DTT |
Escherichia coli |
Substrates and Products (Substrate)
EC Number |
Substrates |
Comment Substrates |
Organism |
Products |
Comment (Products) |
Rev. |
Reac. |
---|
1.3.1.12 |
prephenate + NAD+ |
- |
Escherichia coli |
4-hydroxyphenylpyruvate + NADH + CO2 |
- |
? |
|
1.3.1.12 |
prephenate + NAD+ |
biosynthesis of L-tyrosine |
Escherichia coli |
4-hydroxyphenylpyruvate + NADH + CO2 |
- |
? |
|
Subunits
EC Number |
Subunits |
Comment |
Organism |
---|
1.3.1.12 |
dimer |
2 * 39000-42000, SDS-PAGE |
Escherichia coli |
Synonyms
EC Number |
Synonyms |
Comment |
Organism |
---|
1.3.1.12 |
chorismate mutase-prephenate dehydrogenase bifunctional enzyme |
complex with EC 5.4.99.5 |
Escherichia coli |