EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
1.3.1.79 | L-tyrosine | slightly enhanced activity | Myroides odoratus | |
1.3.1.79 | L-tyrosine | slightly enhanced activity | Flavobacterium suaveolens | |
1.3.1.79 | phenylalanine | slightly enhanced activity | Myroides odoratus | |
1.3.1.79 | phenylalanine | slightly enhanced activity | Flavobacterium suaveolens |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.3.1.79 | L-phenylalanine | - |
Agromyces mediolanus | |
1.3.1.79 | L-phenylalanine | - |
Empedobacter brevis | |
1.3.1.79 | L-phenylalanine | - |
Flavobacterium aquatile | |
1.3.1.79 | L-phenylalanine | - |
[Flavobacterium] lutescens | |
1.3.1.79 | L-phenylalanine | - |
Flavobacterium paucimobilis | |
1.3.1.79 | L-phenylalanine | - |
Novosphingobium capsulatum | |
1.3.1.79 | L-phenylalanine | - |
Sphingomonas paucimobilis | |
1.3.1.79 | L-tyrosine | - |
Agromyces mediolanus | |
1.3.1.79 | L-tyrosine | - |
Empedobacter brevis | |
1.3.1.79 | L-tyrosine | - |
Flavobacterium aquatile | |
1.3.1.79 | L-tyrosine | - |
[Flavobacterium] lutescens | |
1.3.1.79 | L-tyrosine | - |
Flavobacterium paucimobilis | |
1.3.1.79 | L-tyrosine | - |
Novosphingobium capsulatum | |
1.3.1.79 | L-tyrosine | - |
Sphingomonas paucimobilis |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.3.1.12 | prephenate + NAD+ | Sphingomonas paucimobilis | biosynthesis of L-tyrosine | 4-hydroxyphenylpyruvate + NADH + CO2 | - |
? | |
1.3.1.12 | prephenate + NAD+ | Novosphingobium capsulatum | biosynthesis of L-tyrosine | 4-hydroxyphenylpyruvate + NADH + CO2 | - |
? | |
1.3.1.13 | prephenate + NADP+ | Flavobacterium sp. | - |
4-hydroxyphenylpyruvate + CO2 + NADPH | - |
? | |
1.3.1.79 | L-arogenate + NAD+ | Sphingomonas paucimobilis | i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine | L-tyrosine + NADH + CO2 | - |
? | |
1.3.1.79 | L-arogenate + NAD+ | Novosphingobium capsulatum | i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine | L-tyrosine + NADH + CO2 | - |
? | |
1.3.1.79 | L-arogenate + NAD+ | Flavobacterium aquatile | i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine | L-tyrosine + NADH + CO2 | - |
? | |
1.3.1.79 | L-arogenate + NAD+ | Empedobacter brevis | i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine | L-tyrosine + NADH + CO2 | - |
? | |
1.3.1.79 | L-arogenate + NAD+ | Myroides odoratus | i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine | L-tyrosine + NADH + CO2 | - |
? | |
1.3.1.79 | L-arogenate + NAD+ | Flavobacterium suaveolens | i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine | L-tyrosine + NADH + CO2 | - |
? | |
1.3.1.79 | L-arogenate + NAD+ | [Flavobacterium] lutescens | i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine | L-tyrosine + NADH + CO2 | - |
? | |
1.3.1.79 | L-arogenate + NAD+ | Flavobacterium paucimobilis | i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine | L-tyrosine + NADH + CO2 | - |
? | |
1.3.1.79 | L-arogenate + NAD+ | Agromyces mediolanus | i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine | L-tyrosine + NADH + CO2 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.3.1.12 | Novosphingobium capsulatum | - |
- |
- |
1.3.1.12 | Sphingomonas paucimobilis | - |
- |
- |
1.3.1.13 | Flavobacterium sp. | - |
- |
- |
1.3.1.79 | Agromyces mediolanus | - |
- |
- |
1.3.1.79 | Empedobacter brevis | - |
- |
- |
1.3.1.79 | Flavobacterium aquatile | - |
- |
- |
1.3.1.79 | Flavobacterium paucimobilis | - |
- |
- |
1.3.1.79 | Flavobacterium suaveolens | - |
- |
- |
1.3.1.79 | Myroides odoratus | - |
- |
- |
1.3.1.79 | Novosphingobium capsulatum | - |
- |
- |
1.3.1.79 | Sphingomonas paucimobilis | - |
- |
- |
1.3.1.79 | [Flavobacterium] lutescens | - |
- |
- |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.3.1.79 | additional information | - |
- |
Sphingomonas paucimobilis |
1.3.1.79 | additional information | - |
- |
Novosphingobium capsulatum |
1.3.1.79 | additional information | - |
- |
Flavobacterium aquatile |
1.3.1.79 | additional information | - |
- |
Empedobacter brevis |
1.3.1.79 | additional information | - |
- |
Myroides odoratus |
1.3.1.79 | additional information | - |
- |
Flavobacterium suaveolens |
1.3.1.79 | additional information | - |
- |
[Flavobacterium] lutescens |
1.3.1.79 | additional information | - |
- |
Flavobacterium paucimobilis |
1.3.1.79 | additional information | - |
- |
Agromyces mediolanus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.3.1.12 | prephenate + NAD+ | - |
Sphingomonas paucimobilis | 4-hydroxyphenylpyruvate + NADH + CO2 | - |
? | |
1.3.1.12 | prephenate + NAD+ | - |
Novosphingobium capsulatum | 4-hydroxyphenylpyruvate + NADH + CO2 | - |
? | |
1.3.1.12 | prephenate + NAD+ | biosynthesis of L-tyrosine | Sphingomonas paucimobilis | 4-hydroxyphenylpyruvate + NADH + CO2 | - |
? | |
1.3.1.12 | prephenate + NAD+ | biosynthesis of L-tyrosine | Novosphingobium capsulatum | 4-hydroxyphenylpyruvate + NADH + CO2 | - |
? | |
1.3.1.13 | prephenate + NADP+ | - |
Flavobacterium sp. | 4-hydroxyphenylpyruvate + CO2 + NADPH | - |
? | |
1.3.1.79 | L-arogenate + NAD(P)+ | - |
Sphingomonas paucimobilis | L-tyrosine + NAD(P)H + CO2 | - |
? | |
1.3.1.79 | L-arogenate + NAD(P)+ | - |
Novosphingobium capsulatum | L-tyrosine + NAD(P)H + CO2 | - |
? | |
1.3.1.79 | L-arogenate + NAD(P)+ | - |
Flavobacterium aquatile | L-tyrosine + NAD(P)H + CO2 | - |
? | |
1.3.1.79 | L-arogenate + NAD(P)+ | - |
Empedobacter brevis | L-tyrosine + NAD(P)H + CO2 | - |
? | |
1.3.1.79 | L-arogenate + NAD(P)+ | - |
Myroides odoratus | L-tyrosine + NAD(P)H + CO2 | - |
? | |
1.3.1.79 | L-arogenate + NAD(P)+ | - |
Flavobacterium suaveolens | L-tyrosine + NAD(P)H + CO2 | - |
? | |
1.3.1.79 | L-arogenate + NAD(P)+ | - |
[Flavobacterium] lutescens | L-tyrosine + NAD(P)H + CO2 | - |
? | |
1.3.1.79 | L-arogenate + NAD(P)+ | - |
Flavobacterium paucimobilis | L-tyrosine + NAD(P)H + CO2 | - |
? | |
1.3.1.79 | L-arogenate + NAD(P)+ | - |
Agromyces mediolanus | L-tyrosine + NAD(P)H + CO2 | - |
? | |
1.3.1.79 | L-arogenate + NAD+ | i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine | Sphingomonas paucimobilis | L-tyrosine + NADH + CO2 | - |
? | |
1.3.1.79 | L-arogenate + NAD+ | i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine | Novosphingobium capsulatum | L-tyrosine + NADH + CO2 | - |
? | |
1.3.1.79 | L-arogenate + NAD+ | i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine | Flavobacterium aquatile | L-tyrosine + NADH + CO2 | - |
? | |
1.3.1.79 | L-arogenate + NAD+ | i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine | Empedobacter brevis | L-tyrosine + NADH + CO2 | - |
? | |
1.3.1.79 | L-arogenate + NAD+ | i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine | Myroides odoratus | L-tyrosine + NADH + CO2 | - |
? | |
1.3.1.79 | L-arogenate + NAD+ | i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine | Flavobacterium suaveolens | L-tyrosine + NADH + CO2 | - |
? | |
1.3.1.79 | L-arogenate + NAD+ | i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine | [Flavobacterium] lutescens | L-tyrosine + NADH + CO2 | - |
? | |
1.3.1.79 | L-arogenate + NAD+ | i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine | Flavobacterium paucimobilis | L-tyrosine + NADH + CO2 | - |
? | |
1.3.1.79 | L-arogenate + NAD+ | i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine | Agromyces mediolanus | L-tyrosine + NADH + CO2 | - |
? |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.3.1.12 | NAD+ | - |
Sphingomonas paucimobilis | |
1.3.1.12 | NAD+ | - |
Novosphingobium capsulatum | |
1.3.1.79 | NAD+ | - |
Sphingomonas paucimobilis | |
1.3.1.79 | NAD+ | NADP+ is a better electron acceptor than NAD+ | Novosphingobium capsulatum | |
1.3.1.79 | NAD+ | NADP+ is a better electron acceptor than NAD+ | Flavobacterium aquatile | |
1.3.1.79 | NAD+ | NADP+ is a better electron acceptor than NAD+ | Empedobacter brevis | |
1.3.1.79 | NAD+ | NADP+ is a better electron acceptor than NAD+ | Myroides odoratus | |
1.3.1.79 | NAD+ | NADP+ is a better electron acceptor than NAD+ | Flavobacterium suaveolens | |
1.3.1.79 | NAD+ | NADP+ is a better electron acceptor than NAD+ | [Flavobacterium] lutescens | |
1.3.1.79 | NAD+ | NADP+ is a better electron acceptor than NAD+ | Flavobacterium paucimobilis | |
1.3.1.79 | NAD+ | NADP+ is a better electron acceptor than NAD+ | Agromyces mediolanus | |
1.3.1.79 | NADP+ | - |
Sphingomonas paucimobilis | |
1.3.1.79 | NADP+ | NADP+ is a better electron acceptor than NAD+ | Novosphingobium capsulatum | |
1.3.1.79 | NADP+ | NADP+ is a better electron acceptor than NAD+ | Flavobacterium aquatile | |
1.3.1.79 | NADP+ | NADP+ is a better electron acceptor than NAD+ | Empedobacter brevis | |
1.3.1.79 | NADP+ | NADP+ is a better electron acceptor than NAD+ | Myroides odoratus | |
1.3.1.79 | NADP+ | NADP+ is a better electron acceptor than NAD+ | Flavobacterium suaveolens | |
1.3.1.79 | NADP+ | NADP+ is a better electron acceptor than NAD+ | [Flavobacterium] lutescens | |
1.3.1.79 | NADP+ | NADP+ is a better electron acceptor than NAD+ | Flavobacterium paucimobilis | |
1.3.1.79 | NADP+ | NADP+ is a better electron acceptor than NAD+ | Agromyces mediolanus |