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Literature summary extracted from
- The refined structures of a stabilized mutant and of wild-type pyruvate oxidase from Lactobacillus plantarum (1994), J. Mol. Biol., 237, 315-335.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 1.2.3.3 | expression in Escherichia coli | Lactiplantibacillus plantarum |
Crystallization (Commentary)
| EC Number | Crystallization (Comment) | Organism |
|---|---|---|
| 1.2.3.3 | wild-type at 2.5 A resolution, triple mutant at 2.1 A resolution, hanging drop vapour diffusion technique | Lactiplantibacillus plantarum |
Protein Variants
| EC Number | Protein Variants | Comment | Organism |
|---|---|---|---|
| 1.2.3.3 | P178S/S188N/A458V | stabilizes quaternary rather than tertiary structure | Lactiplantibacillus plantarum |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.2.3.3 | Mg2+ | - |
Lactiplantibacillus plantarum |  |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.2.3.3 | pyruvate + phosphate + O2 + H2O | Lactiplantibacillus plantarum | - |
acetyl phosphate + CO2 + H2O2 | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.2.3.3 | Lactiplantibacillus plantarum | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.2.3.3 | pyruvate + phosphate + O2 + H2O | - |
Lactiplantibacillus plantarum | acetyl phosphate + CO2 + H2O2 | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 1.2.3.3 | tetramer | composed of four identical subunits, each subunit binds one FAD and one thiamine diphosphate-Mg2+, analysis from X-ray diffraction data | Lactiplantibacillus plantarum |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.2.3.3 | POX | - |
Lactiplantibacillus plantarum |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.2.3.3 | FAD | - |
Lactiplantibacillus plantarum | |
| 1.2.3.3 | thiamine diphosphate | - |
Lactiplantibacillus plantarum | |
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Release 2023.1 (January 2023)
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