Literature summary extracted from

Hupert, J.; Mobarhan, S.; Layden, T.J.; Papa, V.M.; Lucchesi, D.
In vitro formation of retinoic acid from retinal in rat liver (1991), Biochem. Cell Biol., 69, 509-514.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
1.2.3.1	NAD+	stimulation of retinoic acid formation up to 0.1 mM, more effective than NADH	Rattus sp.
1.2.3.1	NADH	stimulation of retinoic acid formation up to 0.1 mM	Rattus sp.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.2.3.1	DTT	more than 50% inhibition at 1.6 mM	Rattus sp.

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
1.2.3.1	0.25	-	retinal	-	Rattus sp.

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
1.2.3.1	cytoplasm	-	Rattus sp.	5737	-

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.2.3.1	retinal + O2 + H2O	Rattus sp.	-	retinoate + H2O2	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.2.3.1	Rattus sp.	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.2.3.1	liver	-	Rattus sp.	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.2.3.1	retinal + O2 + H2O	-	Rattus sp.	retinoate + H2O2	-	?

pH Optimum

EC Number	pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
1.2.3.1	7.7	9.7	-	Rattus sp.

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Release 2023.1 (January 2023)