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Literature summary extracted from

  • Fujioka, M.; Morino, Y.; Wada, H.
    Metabolism of phenylalanine (Achromobacter eurydice) (1970), Methods Enzymol., 17A, 585-596.
No PubMed abstract available

General Stability

EC Number General Stability Organism
1.2.1.39 unstable after dilution Achromobacter eurydice

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.2.1.39 K+ above 1 M Achromobacter eurydice
1.2.1.39 N-ethylmaleimide
-
 Achromobacter eurydice
1.2.1.39 p-chloromercuribenzoate
-
 Achromobacter eurydice

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.2.1.39 0.07
-
 NAD+
-
 Achromobacter eurydice

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.2.1.39 Cs+ monovalent cation required. K+ , Rb+ , Na+, Li+, NH4+ and Cs+ activate in this order Achromobacter eurydice
1.2.1.39 K+ monovalent cation required. K+ , Rb+ , Na+, Li+, NH4+ and Cs+ activate in this order Achromobacter eurydice
1.2.1.39 Li+ monovalent cation required. K+ , Rb+ , Na+, Li+, NH4+ and Cs+ activate in this order Achromobacter eurydice
1.2.1.39 additional information divalent cations (Mg2+, Ca2+) are inactive Achromobacter eurydice
1.2.1.39 Na+ monovalent cation required. K+ , Rb+ , Na+, Li+, NH4+ and Cs+ activate in this order Achromobacter eurydice
1.2.1.39 NH4+ monovalent cation required. K+ , Rb+ , Na+, Li+, NH4+ and Cs+ activate in this order Achromobacter eurydice
1.2.1.39 Rb+ monovalent cation required. K+ , Rb+ , Na+, Li+, NH4+ and Cs+ activate in this order Achromobacter eurydice

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.39 phenylacetaldehyde + NAD+ + H2O Achromobacter eurydice inducible enzyme appears when cells are grown on L-phenylalanine or on L-tryptophan as sole source of carbon ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.39 Achromobacter eurydice
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.2.1.39
-
 Achromobacter eurydice

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.2.1.39 19
-
-
 Achromobacter eurydice

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.39 indoleacetaldehyde + NAD+ + H2O slow reaction Achromobacter eurydice indoleacetate + NADH
-
 ?
1.2.1.39 n-butyraldehyde + NAD+ + H2O slow reaction Achromobacter eurydice n-butyrate + NADH
-
 ?
1.2.1.39 phenylacetaldehyde + NAD+ + H2O highly specific for phenylacetaldehyde, NADP+ is about 1% as active as NAD+ Achromobacter eurydice phenylacetate + NADH + H+
-
 ir
1.2.1.39 phenylacetaldehyde + NAD+ + H2O inducible enzyme appears when cells are grown on L-phenylalanine or on L-tryptophan as sole source of carbon Achromobacter eurydice ?
-
 ?
1.2.1.39 propionaldehyde + NAD+ + H2O slow reaction Achromobacter eurydice propionate + NADH
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.2.1.39 8.9
-
-
 Achromobacter eurydice

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
1.2.1.39 additional information
-
 unstable after dilution, especially in alkaline medium Achromobacter eurydice

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.39 NAD+ NADP+ is about 1% as active as NAD+ Achromobacter eurydice