EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
1.2.1.21 | pyridoxal | approx. 0.1 mM, 1.4fold increase in activity of isozyme A | Escherichia coli | |
1.2.1.21 | pyridoxal 5'-phosphate | approx. 0.1 mM, 1.5fold increase in activity of isozyme B | Escherichia coli | |
1.2.1.21 | pyridoxine | 0.1 mM, 1.5fold increase in activity of isozyme B | Escherichia coli |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.2.1.21 | pyridoxal | 0.01 mM, 40% inhibition of total enzyme activity in cell extracts | Escherichia coli | |
1.2.1.21 | pyridoxamine | approx. 0.1 mM, 22% inhibition of isozyme A | Escherichia coli | |
1.2.1.21 | pyridoxamine phosphate | approx. 0.1 mM, 23% inhibition of isozyme A | Escherichia coli | |
1.2.1.21 | pyridoxine | approx. 0.1 mM, 33% inhibition of isozyme C, 0.39 mM, 50% inhibition | Escherichia coli | |
1.2.1.21 | pyridoxine phosphate | approx. 0.1 mM, 23% inhibition of isozyme C | Escherichia coli |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.2.1.21 | Escherichia coli | - |
- |
- |
1.2.1.21 | Escherichia coli B WG1 | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.2.1.21 | glycolaldehyde + NAD+ + H2O | - |
Escherichia coli | glycolate + NADH | - |
? | |
1.2.1.21 | glycolaldehyde + NAD+ + H2O | - |
Escherichia coli B WG1 | glycolate + NADH | - |
? |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.2.1.21 | 0.33 | - |
pyridoxine | inhibition of isozyme C | Escherichia coli |