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Literature summary extracted from

  • Kish, M.M.; Viola, R.E.
    Oxyanion specificity of L-Aspartate-beta-semialdehyde dehydrogenase (1999), Inorg. Chem., 38, 818-820.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.2.1.11 Periodate
-
 Escherichia coli
1.2.1.11 perrhenate very weak inhibitor Escherichia coli
1.2.1.11 phosphonate weak inhibitor Escherichia coli
1.2.1.11 tellurate
-
 Escherichia coli
1.2.1.11 tungstate
-
 Escherichia coli

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.2.1.11 0.14
-
 vanadate
-
 Escherichia coli
1.2.1.11 1.6
-
 arsenate
-
 Escherichia coli
1.2.1.11 2.9
-
 phosphate
-
 Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.11 L-4-aspartyl phosphate + NADPH Escherichia coli
-
 L-aspartate 4-semialdehyde + phosphate + NADP+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.11 Escherichia coli
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.11 L-4-aspartyl phosphate + NADPH
-
 Escherichia coli L-aspartate 4-semialdehyde + phosphate + NADP+
-
 ?
1.2.1.11 L-aspartate 4-semialdehyde + arsenate + NADP+
-
 Escherichia coli ?
-
 r
1.2.1.11 L-aspartate 4-semialdehyde + phosphate + NADP+
-
 Escherichia coli L-4-aspartyl phosphate + NADPH
-
 r
1.2.1.11 L-aspartate 4-semialdehyde + vanadate + NADP+
-
 Escherichia coli ?
-
 r
1.2.1.11 additional information the putative phosphate side contains arginine and a lysine that can provide electrostratic attraction to bind an oxyanion Escherichia coli ?
-
 ?
1.2.1.11 additional information the kinetic parameters with arsenate are comparable to those of phosphate, vanadate is an excellent substrate for the enzyme Escherichia coli ?
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.11 NADP+
-
 Escherichia coli
1.2.1.11 NADPH
-
 Escherichia coli

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.2.1.11 0.22
-
 Periodate
-
 Escherichia coli
1.2.1.11 11
-
 tellurate
-
 Escherichia coli
1.2.1.11 17
-
 phosphonate
-
 Escherichia coli
1.2.1.11 26
-
 tungstate
-
 Escherichia coli
1.2.1.11 140
-
 perrhenate
-
 Escherichia coli