EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.14.14.94 | 5-aminosalicylic acid | 50% inhibition at 0.05 mM | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.14.94 | (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + [reduced NADPH-hemoprotein reductase] + O2 | Homo sapiens | inactivation of leukotriene B4, a mediator of inflammation | (6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
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EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.14.94 | Homo sapiens | - |
- |
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EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.14.14.94 | leukocyte | polymorphonuclear | Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.14.94 | (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + [reduced NADPH-hemoprotein reductase] + O2 | inactivation of leukotriene B4, a mediator of inflammation | Homo sapiens | (6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
1.14.14.94 | leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2 | leukotriene B4 is identical with (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate | Homo sapiens | 20-hydroxy-leukotriene B4 + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |