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Literature summary extracted from

  • Ameyama, M.; Shinagawa, E.; Matsushita, K.; Takimoto, K.; Nakashima, K.; Adachi, O.
    Mammalian choline dehydrogenase is a quinoprotein (1985), Agric. Biol. Chem., 49, 3623-3626.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.1.99.1 pyrroloquinoline quinone as prosthetic group Canis lupus familiaris

General Stability

EC Number General Stability Organism
1.1.99.1 detergents, e.g. Brij 58, Triton X-100, cholate, deoxycholate or beta-octylglucoside stabilize Canis lupus familiaris

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.99.1 Semicarbazide
-
 Canis lupus familiaris

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.99.1 4.8
-
 choline
-
 Canis lupus familiaris

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.1.99.1 mitochondrion
-
 Canis lupus familiaris 5739
-

Organism

EC Number Organism UniProt Comment Textmining
1.1.99.1 Canis lupus familiaris
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.99.1 using 0.5% Brij 58 treatment, column chromatography on DEAE-cellulose and gel filtration on Toyopearl HW-60S Canis lupus familiaris

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.99.1 liver
-
 Canis lupus familiaris
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.99.1 choline + acceptor electron acceptor: 2,6-dichlorophenolindophenol Canis lupus familiaris betaine aldehyde + reduced acceptor
-
 ?
1.1.99.1 choline + acceptor electron acceptor: phenazine methosulfate Canis lupus familiaris betaine aldehyde + reduced acceptor
-
 ?
1.1.99.1 choline + acceptor choline is the sole substrate Canis lupus familiaris betaine aldehyde + reduced acceptor
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.99.1 7.5 8
-
 Canis lupus familiaris

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.99.1 pyrroloquinoline quinone as prosthetic group Canis lupus familiaris