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Literature summary extracted from
- Metabolites of p-aminobenzoic acid. 5. Isolation and properties of p-aminobenzyl alcohol dehydrogenase (1973), Biochim. Biophys. Acta, 327, 11-19.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.91 | 1,10-phenanthroline | - |
Mycobacterium tuberculosis |  |
| 1.1.1.91 | p-chloromercuribenzoate | - |
Mycobacterium tuberculosis | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.1.1.91 | 0.04 | - |
p-aminobenzyl alcohol | - |
Mycobacterium tuberculosis | |
| 1.1.1.91 | 0.057 | - |
benzyl alcohol | - |
Mycobacterium tuberculosis | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.1.1.91 | Mycobacterium tuberculosis | - |
American Type Culture Collection No.607 | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.1.1.91 | - |
Mycobacterium tuberculosis |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.91 | benzyl alcohol + NADP+ | - |
Mycobacterium tuberculosis | benzaldehyde + NADPH | - |
r | |
| 1.1.1.91 | p-aminobenzyl alcohol + NADP+ | - |
Mycobacterium tuberculosis | p-aminobenzaldehyd + NADPH | - |
r | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.91 | 6.8 | - |
in imidazole buffer | Mycobacterium tuberculosis |
pH Range
| EC Number | pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.91 | 6.2 | 7.2 | in imidazole buffer | Mycobacterium tuberculosis |
| 1.1.1.91 | 7 | 8 | in phosphate buffer, activity of the enzyme is only one-half that shown in imidazole buffer | Mycobacterium tuberculosis |
| 1.1.1.91 | 7.9 | 8.5 | in Tris buffer, activity is about 40% as in imidazole buffer | Mycobacterium tuberculosis |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.91 | NAD+ | enzyme utizilizes either NAD+ or NADP+ in the oxidation | Mycobacterium tuberculosis | |
| 1.1.1.91 | NADP+ | enzyme utizilizes either NAD+ or NADP+ in the oxidation | Mycobacterium tuberculosis | |
| 1.1.1.91 | NADPH | - |
Mycobacterium tuberculosis | |
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