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Literature summary extracted from

  • Wu, B.; Zhang, Y.; Wang, P.G.
    Identification and characterization of GDP-D-mannose 4,6-dehydratase and GDP-L-fucose synthetase in a GDP-L-fucose biosynthetic gene cluster from Helicobacter pylori (2001), Biochem. Biophys. Res. Commun., 285, 364-371.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.271
-
 Helicobacter pylori

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.271 0.064
-
 GDP-4-keto-6-deoxy-D-mannose
-
 Helicobacter pylori

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.271 Helicobacter pylori
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.271 GDP-4-keto-6-deoxy-D-mannose + NADPH
-
 Helicobacter pylori GDP-6-deoxy-L-galactose + NADP+
-
 ?

Subunits

EC Number Subunits Comment Organism
1.1.1.271 dimer homodimer Helicobacter pylori

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.1.1.271 0.75
-
 GDP-4-keto-6-deoxy-D-mannose
-
 Helicobacter pylori

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.271 8
-
-
 Helicobacter pylori

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.271 NADH less efficient than with NADPH Helicobacter pylori
1.1.1.271 NADPH
-
 Helicobacter pylori