Literature summary extracted from

Chang, S.; Duerr, B.; Serif, G.
An epimerase-reductase in L-fucose synthesis (1988), J. Biol. Chem., 263, 1693-1697.

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
1.1.1.271	0.014	-	GDP-4-keto-6-deoxy-D-mannose	-	Sus scrofa
1.1.1.271	0.023	-	NADH	-	Sus scrofa

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
1.1.1.271	31500	-	SDS-PAGE	Sus scrofa
1.1.1.271	63100	-	gel filtration	Sus scrofa

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.1.1.271	Sus scrofa	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
1.1.1.271	homogeneity	Sus scrofa

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.1.1.271	thyroid gland	-	Sus scrofa	-

Specific Activity [micromol/min/mg]

EC Number	Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
1.1.1.271	0.194	-	-	Sus scrofa

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.1.1.271	GDP-4-dehydro-6-deoxy-alpha-D-mannose + NADH + H+	-	Sus scrofa	GDP-beta-L-fucose + NAD+	-	r
1.1.1.271	GDP-4-keto-6-deoxy-D-mannose + NADPH	enzyme uses NADH as cofactor	Sus scrofa	GDP-6-deoxy-L-galactose + NADP+	-	?

Subunits

EC Number	Subunits	Comment	Organism
1.1.1.271	dimer	two similar subunits	Sus scrofa

pH Optimum

EC Number	pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
1.1.1.271	6.9	-	-	Sus scrofa

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.1.1.271	NADH	-	Sus scrofa

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Release 2023.1 (January 2023)