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Literature summary extracted from

  • Watanabe, K.; Shimizu, T.; Hayaishi, O.
    Enzymic conversion of prostaglandin D2 to F2alpha in the rat lung (1981), Biochem. Int., 2, 603-610.
No PubMed abstract available

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.188 0.067
-
 NADPH
-
 Rattus norvegicus
1.1.1.188 2
-
 Prostaglandin D2
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.1.1.188 cytosol
-
 Rattus norvegicus 5829
-

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.188 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.188 adrenal gland
-
 Rattus norvegicus
-
1.1.1.188 heart
-
 Rattus norvegicus
-
1.1.1.188 lung
-
 Rattus norvegicus
-
1.1.1.188 stomach
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.188 (5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate + NADPH
-
 Rattus norvegicus (5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate + NADP+
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.188 NADH with NADH as cofactor no activity observed Rattus norvegicus
1.1.1.188 NADPH
-
 Rattus norvegicus