EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.14.15.15 | 1,10-phenanthroline | - |
Homo sapiens | |
1.14.15.15 | Isobutyramide | - |
Homo sapiens | |
1.14.15.15 | additional information | product inhibition | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.15.15 | 5beta-cholestane-3alpha,7alpha,12alpha,26-tetraol + reduced adrenodoxin + O2 | Homo sapiens | - |
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al + oxidized adrenodoxin + H2O | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.15.15 | Homo sapiens | - |
both alcohol:NAD+ oxidoreductase activity, EC 1.1.1.1, and 5beta-cholestane-3alpha,7alpha,12alpha,26-tetraol:NAD+ 26-oxidoreductase activity, EC 1.1.1.161, are catalyzed by the same active side of the same enzyme protein | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.14.15.15 | - |
Homo sapiens |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.14.15.15 | liver | - |
Homo sapiens | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.14.15.15 | 0.672 | - |
- |
Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.15.15 | 5beta-cholestane-3alpha,7alpha,12alpha,26-tetraol + reduced adrenodoxin + O2 | - |
Homo sapiens | 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al + oxidized adrenodoxin + H2O | - |
? |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
1.14.15.15 | 10.6 | - |
- |
Homo sapiens |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
1.14.15.15 | 8.3 | 11.2 | pH 8.3: about 20% of activity maximum, pH 11.2: about 60% of activity maximum | Homo sapiens |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.14.15.15 | NAD+ | - |
Homo sapiens |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.14.15.15 | 2 | - |
Isobutyramide | - |
Homo sapiens |