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Literature summary extracted from

  • Herbert, D.; Alban, C.; Cole, D.J.; Pallett, K.E.; Harwood, J.L.
    Characteristics of two forms of acetyl-CoA carboxylase from maize leaves (1994), Biochem. Soc. Trans., 22, 261S.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.4.1.2 Quizalofop mesophyll chloroplast isoform reveals 1000fold greater sensitivity than non-mesophyll chloroplast isoform Zea mays

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.4.1.2 0.04
-
 ATP non-mesophyll chloroplast isoform Zea mays
6.4.1.2 0.05
-
 acetyl-CoA mesophyll chloroplast isoform Zea mays
6.4.1.2 0.09
-
 acetyl-CoA non-mesophyll chloroplast isoform Zea mays
6.4.1.2 0.095
-
 acetyl-CoA mesophyll chloroplast isoform Zea mays
6.4.1.2 0.6
-
 HCO3- non-mesophyll chloroplast isoform Zea mays
6.4.1.2 1.2
-
 acetyl-CoA mesophyll chloroplast isoform Zea mays

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
6.4.1.2 chloroplast 2 isoforms: non-mesophyll chloroplast form and mesophyll chloroplast form Zea mays 9507
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
6.4.1.2 220000
-
 2 * 220000, non-mesophyll chloroplast isoform, SDS-PAGE Zea mays
6.4.1.2 230000
-
 2 * 230000, mesophyll chloroplast isoform, SDS-PAGE Zea mays

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.4.1.2 ATP + acetyl-CoA + HCO3- Zea mays key role in lipid metabolism ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.4.1.2 Zea mays
-
 2 isoforms: non-mesophyll chloroplast form and mesophyll chloroplast form
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.4.1.2 2 isoforms: non-mesophyll chloroplast form and mesophyll chloroplast form Zea mays

Reaction

EC Number Reaction Comment Organism Reaction ID
6.4.1.2 ATP + acetyl-CoA + hydrogencarbonate = ADP + phosphate + malonyl-CoA non-ordered ter ter mechanism Zea mays
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.4.1.2 leaf 2 isoforms: non-mesophyll chloroplast form and mesophyll chloroplast form Zea mays
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.4.1.2 ATP + acetyl-CoA + HCO3-
-
 Zea mays ADP + phosphate + malonyl-CoA
-
 ?
6.4.1.2 ATP + acetyl-CoA + HCO3- key role in lipid metabolism Zea mays ?
-
 ?

Subunits

EC Number Subunits Comment Organism
6.4.1.2 dimer 2 * 220000, non-mesophyll chloroplast isoform, SDS-PAGE Zea mays
6.4.1.2 dimer 2 * 230000, mesophyll chloroplast isoform, SDS-PAGE Zea mays

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
6.4.1.2 7.5
-
 non-mesophyll chloroplast isoform Zea mays
6.4.1.2 8 8.5 mesophyll chloroplast isoform Zea mays