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Literature summary extracted from
- Preparation and assay of prostacyclin synthase (1982), Methods Enzymol., 86, 91-99.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.3.99.4 | 15-hydroperoxy-5,8,11,13-eicosatetraenoic acid | - |
Sus scrofa |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.3.99.4 | Sus scrofa | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 5.3.99.4 | partial | Sus scrofa |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 5.3.99.4 | artery | vascular | Sus scrofa | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 5.3.99.4 | additional information | - |
assay methods | Sus scrofa |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.3.99.4 | prostaglandin G2 | - |
Sus scrofa | prostaglandin I2 + 15-hydroperoxyprostacyclin | 15-hydroperoxyprostacyclin decomposes to 6,15-diketo-prostaglandin F1alpha | ? | |
| 5.3.99.4 | Prostaglandin H2 | - |
Sus scrofa | Prostaglandin I2 | prostaglandin I2 | ? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 5.3.99.4 | 6.8 | 7.5 | - |
Sus scrofa |
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Release 2023.1 (January 2023)
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