Literature summary extracted from

Terashita, Z.i.; Nishikawa, K.; Terao, S.; Nakagawa, M.; Hino, T.
A specific prostaglandin I2 synthetase inhibitor, 3-hydroperoxy-3-methyl-2-phenyl-3H-indole (1979), Biochem. Biophys. Res. Commun., 91, 72-78.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
5.3.99.4	15-hydroperoxy-5,8,11,13-eicosatetraenoic acid	-	Bos taurus
5.3.99.4	3-hydroperoxy-3-methyl-2-phenyl-3H-indole	-	Bos taurus
5.3.99.4	arachidonic acid	-	Bos taurus
5.3.99.4	Hydroperoxy-fatty acids	lipoxygenase products	Bos taurus
5.3.99.4	tranylcypromine	-	Bos taurus

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
5.3.99.4	microsome	-	Bos taurus	-	-

Organism

EC Number	Organism	UniProt	Comment	Textmining
5.3.99.4	Bos taurus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
5.3.99.4	aorta	-	Bos taurus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5.3.99.4	Prostaglandin H2	-	Bos taurus	Prostaglandin I2	prostaglandin I2	?

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Release 2023.1 (January 2023)