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Literature summary extracted from

  • Mannervik, B.; Aronsson, A.C.; Tibbelin, G.
    Glyoxalase I from human erythrocytes (1982), Methods Enzymol., 90, 535-541.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.4.1.5 S-p-bromobenzylglutathione
-
 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.4.1.5 0.04
-
 Phenylglyoxal
-
 Homo sapiens
4.4.1.5 0.13
-
 methylglyoxal
-
 Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.4.1.5 46000
-
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
4.4.1.5 Homo sapiens
-
 3 isoenzymes
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.4.1.5
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.4.1.5 erythrocyte
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.4.1.5 1150
-
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.4.1.5 glutathione + methylglyoxal
-
 Homo sapiens S-lactoylglutathione
-
 ?
4.4.1.5 glutathione + phenylglyoxal
-
 Homo sapiens S-mandeloylglutathione
-
 ?

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
4.4.1.5 1070
-
 Phenylglyoxal
-
 Homo sapiens
4.4.1.5 1130
-
 methylglyoxal
-
 Homo sapiens