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Literature summary extracted from

  • Yamamoto, S.; Imamura, T.; Kusaba, K.; Shinoda, S.
    Purification and some properties of inducible lysine decarboxylase from Vibrio parahaemolyticus (1991), Chem. Pharm. Bull., 39, 3067-3070.
    View publication on PubMed

General Stability

EC Number General Stability Organism
4.1.1.18 dithiothreitol is required for stabilization during purification and storage Vibrio parahaemolyticus
4.1.1.18 pyridoxal 5'-phosphate is indispensable for stability Vibrio parahaemolyticus

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.18 6-aminohexanoate
-
 Vibrio parahaemolyticus
4.1.1.18 alpha-Difluoromethylcadaverine
-
 Vibrio parahaemolyticus
4.1.1.18 alpha-Monofluoromethylcadaverine
-
 Vibrio parahaemolyticus
4.1.1.18 alpha-Trifluoromethylcadaverine
-
 Vibrio parahaemolyticus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.18 3.2
-
 L-Lys
-
 Vibrio parahaemolyticus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.1.18 79000
-
 7 * 79000, SDS-PAGE Vibrio parahaemolyticus
4.1.1.18 531000
-
 gel filtration Vibrio parahaemolyticus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.18 L-Lys Vibrio parahaemolyticus inducible enzyme ?
-
 ?
4.1.1.18 L-Lys Vibrio parahaemolyticus AQ 3627 inducible enzyme ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.18 Vibrio parahaemolyticus
-
-
-
4.1.1.18 Vibrio parahaemolyticus AQ 3627
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.18
-
 Vibrio parahaemolyticus

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.1.1.18 additional information
-
-
 Vibrio parahaemolyticus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.18 delta-Hydroxylysine 17% of the activity with L-Lys Vibrio parahaemolyticus 1,5-Diamino-2-hydroxypentane + CO2
-
 ?
4.1.1.18 delta-Hydroxylysine 17% of the activity with L-Lys Vibrio parahaemolyticus AQ 3627 1,5-Diamino-2-hydroxypentane + CO2
-
 ?
4.1.1.18 L-Lys
-
 Vibrio parahaemolyticus Cadaverine + CO2
-
 ?
4.1.1.18 L-Lys
-
 Vibrio parahaemolyticus AQ 3627 Cadaverine + CO2
-
 ?
4.1.1.18 L-Lys inducible enzyme Vibrio parahaemolyticus ?
-
 ?
4.1.1.18 L-Lys inducible enzyme Vibrio parahaemolyticus AQ 3627 ?
-
 ?
4.1.1.18 S-Aminoethyl-L-Cys 23% of the activity with L-Lys Vibrio parahaemolyticus 1-Amino-2-(S-aminoethyl)mercaptoethane + CO2
-
 ?
4.1.1.18 S-Aminoethyl-L-Cys 23% of the activity with L-Lys Vibrio parahaemolyticus AQ 3627 1-Amino-2-(S-aminoethyl)mercaptoethane + CO2
-
 ?

Subunits

EC Number Subunits Comment Organism
4.1.1.18 heptamer 7 * 79000, SDS-PAGE Vibrio parahaemolyticus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
4.1.1.18 45 50
-
 Vibrio parahaemolyticus

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
4.1.1.18 20 80 20°C: about 25% of maximal activity, 80°C: about 95% of maximal activity Vibrio parahaemolyticus

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
4.1.1.18 80
-
 pH 5.5, 10 min, 35% loss of activity Vibrio parahaemolyticus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.1.18 5.5
-
-
 Vibrio parahaemolyticus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
4.1.1.18 4.5 7 pH 4.5: about 35% of maximal activity, pH 7.0: about 60% of maximal activity Vibrio parahaemolyticus

Cofactor

EC Number Cofactor Comment Organism Structure
4.1.1.18 pyridoxal 5'-phosphate required as cofactor Vibrio parahaemolyticus