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Literature summary extracted from

  • Boeker, E.A.; Fischer, E.H.
    Lysine decarboxylase (Escherichia coli B) (1983), Methods Enzymol., 94, 180-184.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.18 NaBH4
-
Escherichia coli

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.18 1.5
-
L-Lys
-
Escherichia coli
4.1.1.18 3.4
-
S-aminoethyl-L-Cys
-
Escherichia coli
4.1.1.18 7
-
delta-hydroxylysine
-
Escherichia coli

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.1.18 80000
-
x * 80000, equilibrium ultracentrifugation in 6 M guanidine-HCl, SDS-PAGE. Association of the dimeric form to the decamer is concomitant with the increase in ionic strength Escherichia coli
4.1.1.18 154000
-
dimeric enzyme form, sedimentation data Escherichia coli
4.1.1.18 730000
-
decameric enzyme form, sedimentation data Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.18 Escherichia coli
-
-
-
4.1.1.18 Escherichia coli B / ATCC 11303
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.18
-
Escherichia coli

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.1.1.18 1000
-
-
Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.18 delta-Hydroxylysine 25% of the activity with L-Lys Escherichia coli 1,5-Diamino-2-hydroxypentane + CO2
-
?
4.1.1.18 delta-Hydroxylysine 25% of the activity with L-Lys Escherichia coli B / ATCC 11303 1,5-Diamino-2-hydroxypentane + CO2
-
?
4.1.1.18 L-Lys
-
Escherichia coli Cadaverine + CO2
-
?
4.1.1.18 L-Lys
-
Escherichia coli B / ATCC 11303 Cadaverine + CO2
-
?
4.1.1.18 S-Aminoethyl-L-Cys 15% of the activity with L-Lys Escherichia coli 1-Amino-2-(S-aminoethyl)mercaptoethane + CO2
-
?
4.1.1.18 S-Aminoethyl-L-Cys 15% of the activity with L-Lys Escherichia coli B / ATCC 11303 1-Amino-2-(S-aminoethyl)mercaptoethane + CO2
-
?

Subunits

EC Number Subunits Comment Organism
4.1.1.18 ? x * 80000, equilibrium ultracentrifugation in 6 M guanidine-HCl, SDS-PAGE. Association of the dimeric form to the decamer is concomitant with the increase in ionic strength Escherichia coli

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.1.18 5.7
-
-
Escherichia coli