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Literature summary extracted from

  • Rodd, D.; Hersh, L.B.
    Endopeptidase 24.16B. A new variant of endopeptidase 24.16 (1995), J. Biol. Chem., 270, 10056-10061.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.16 1,10-phenanthroline
-
 Rattus norvegicus
3.4.24.16 EDTA
-
 Rattus norvegicus
3.4.24.16 N-[1-(RS)-carboxy-3-phenylpropyl]-Ala-Ala-Phe-4-aminobenzoate
-
 Rattus norvegicus
3.4.24.16 Pro-Ile
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.24.16 additional information
-
 additional information Km-values for the reaction with angiotensin I analogs Rattus norvegicus
3.4.24.16 0.007
-
 Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile
-
 Rattus norvegicus
3.4.24.16 0.013
-
 Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg
-
 Rattus norvegicus
3.4.24.16 0.041
-
 Tyr-Gly-Gly-Phe-Leu-Arg-Arg
-
 Rattus norvegicus
3.4.24.16 0.085
-
 Tyr-Gly-Gly-Phe-Leu-Arg
-
 Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.16 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.24.16
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.16 testis
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.24.16 6.9
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.16 Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 + H2O
-
 Rattus norvegicus Arg-Pro-Lys-Pro-Gln + Gln-Phe-Phe-Gly-Leu-Met-NH2 + Arg-Pro-Lys-Pro-Gln-Gln + Phe-Phe-Gly-Leu-Met-NH2 + Arg-Pro-Lys-Pro
-
 ?
3.4.24.16 Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu + H2O
-
 Rattus norvegicus Asp-Arg-Val-Tyr-Ile-His-Pro + Phe-His-Leu
-
 ?
3.4.24.16 pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu + H2O
-
 Rattus norvegicus pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro + Tyr-Ile-Leu
-
 ?
3.4.24.16 Tyr-Gly-Gly-Phe-Leu-Arg + H2O
-
 Rattus norvegicus Tyr-Gly-Gly-Phe + Leu-Arg
-
 ?
3.4.24.16 Tyr-Gly-Gly-Phe-Leu-Arg-Arg + H2O cleavage sites: Phe4-Leu5, Leu5-Arg6 Rattus norvegicus ?
-
 ?
3.4.24.16 Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile + H2O
-
 Rattus norvegicus Tyr-Gly-Gly-Phe-Leu + Arg-Arg-Ile
-
 ?
3.4.24.16 Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile + H2O cleavage sites: Leu-5-Arg6, Arg6-Arg7 Rattus norvegicus ?
-
 ?
3.4.24.16 Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg + H2O
-
 Rattus norvegicus Tyr-Gly-Gly-Phe-Leu-Arg-Arg + Ile-Arg
-
 ?

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3.4.24.16 additional information
-
 additional information turnover-numbers for the reaction with angiotensin I analogs Rattus norvegicus
3.4.24.16 0.827
-
 Tyr-Gly-Gly-Phe-Leu-Arg
-
 Rattus norvegicus
3.4.24.16 1.5
-
 Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg
-
 Rattus norvegicus
3.4.24.16 1.94
-
 Tyr-Gly-Gly-Phe-Leu-Arg-Arg
-
 Rattus norvegicus
3.4.24.16 2.52
-
 Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile
-
 Rattus norvegicus