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Literature summary extracted from

  • Kohn, L.D.; Isersky, C.; Zupnik, J.; Lenaers, A.; Lee, G.; Lapiere, C.M.
    Calf tendon procollagen peptidase: its purification and endopeptidase mode of action (1974), Proc. Natl. Acad. Sci. USA, 71, 40-44.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.14 2-mercaptoethanol
-
 Bos taurus
3.4.24.14 glutathione
-
 Bos taurus
3.4.24.14 Mg2+
-
 Bos taurus
3.4.24.14 Mn2+
-
 Bos taurus
3.4.24.14 p-hydroxymercuribenzoate
-
 Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.24.14 0.001
-
 propeptide of collagen alpha-1 chain
-
 Bos taurus
3.4.24.14 0.001
-
 propeptide of collagen alpha-2 chain
-
 Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.24.14 procollagen I + H2O Bos taurus
-
 ?
-
 ?
3.4.24.14 procollagen II + H2O Bos taurus
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.14 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.24.14
-
 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.14 tendon
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.14 procollagen I + H2O
-
 Bos taurus pCCollagen I + oligopeptide partially processed procollagen containing only the C-propeptides ?
3.4.24.14 procollagen I + H2O
-
 Bos taurus ?
-
 ?
3.4.24.14 procollagen II + H2O
-
 Bos taurus pCCollagen II + oligopeptide partially processed procollagen containing only the C-propeptides ?
3.4.24.14 procollagen II + H2O
-
 Bos taurus ?
-
 ?
3.4.24.14 propeptide of collagen alpha-1 chain + H2O
-
 Bos taurus ?
-
 ?
3.4.24.14 propeptide of collagen alpha-2 chain + H2O
-
 Bos taurus ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.24.14 7 7.5 procollagen I Bos taurus