EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.24.12 | 1,10-phenanthroline | - |
Hemicentrotus pulcherrimus | |
3.4.24.12 | alpha2-Macroglobulin | - |
Hemicentrotus pulcherrimus | |
3.4.24.12 | chymostatin | slight | Hemicentrotus pulcherrimus | |
3.4.24.12 | EDTA | - |
Hemicentrotus pulcherrimus | |
3.4.24.12 | EGTA | - |
Hemicentrotus pulcherrimus | |
3.4.24.12 | pepstatin | slight | Hemicentrotus pulcherrimus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.24.12 | Hemicentrotus pulcherrimus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.4.24.12 | - |
Hemicentrotus pulcherrimus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.24.12 | hatching liquid | - |
Hemicentrotus pulcherrimus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.24.12 | Ala-Ser-Thr-Thr-Thr-Asn-Tyr-Thr + H2O | i.e. peptide T, partial cleavage at Asn6-Tyr7 | Hemicentrotus pulcherrimus | Ala-Ser-Thr-Thr-Thr-Asn + Tyr-Thr | - |
? | |
3.4.24.12 | Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 + H2O | i.e. substance P | Hemicentrotus pulcherrimus | Arg-Pro-Lys-Pro-Gln-Gln + Phe-Phe-Gly-Leu-Met-NH2 | - |
? | |
3.4.24.12 | Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg + H2O | i.e. bradykinin, partial cleavage at Pro7-Phe8 | Hemicentrotus pulcherrimus | Arg-Pro-Pro-Gly-Phe-Ser-Pro + Phe-Arg | - |
? | |
3.4.24.12 | Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu + H2O | i.e. angiotensin I, partial cleavage at Pro7-Phe8 | Hemicentrotus pulcherrimus | Asp-Arg-Val-Tyr-Ile-His-Pro + Phe-His-Leu | - |
? | |
3.4.24.12 | fertilization envelope + H2O | enzyme exhibits a unique species specificity, it can not dissolve the fertilization envelope of Anthocidaris crassispina, a species of a neighboring taxonomical family, but can dissolve that of more distantly related species, even if with less efficiency | Hemicentrotus pulcherrimus | ? | - |
? | |
3.4.24.12 | Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-NH2 + H2O | i.e. mastoparan, clevage sites: Asn2-Leu3, 100%, Ala7-Ala8, 100%, Ala10-Lys11, 47%, and Lys12-Ile13, 47% | Hemicentrotus pulcherrimus | ? | - |
? | |
3.4.24.12 | additional information | preferentially cleaves the peptide bond on the amino side of bulky hydrophobic residues, -Leu, -Ile, and -Phe as well as -Tyr | Hemicentrotus pulcherrimus | ? | - |
? | |
3.4.24.12 | neurotensin + H2O | - |
Hemicentrotus pulcherrimus | ? | - |
? | |
3.4.24.12 | physalaemin + H2O | - |
Hemicentrotus pulcherrimus | ? | - |
? | |
3.4.24.12 | snake venom alpha-protease | poor substrate | Hemicentrotus pulcherrimus | ? | - |
? | |
3.4.24.12 | thermolysin + H2O | poor substrate | Hemicentrotus pulcherrimus | ? | - |
? | |
3.4.24.12 | Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys + H2O | i.e. dynorphin A(1-13), partial cleavage at Phe4-Leu5 | Hemicentrotus pulcherrimus | Tyr-Gly-Gly-Phe + Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys | - |
? | |
3.4.24.12 | Tyr-Gly-Gly-Phe-Leu-Arg-Lys-Tyr-Pro + H2O | i.e. beta-neoendorphin, partial cleavage at Phe4-Leu5 | Hemicentrotus pulcherrimus | Tyr-Gly-Gly-Phe + Leu-Arg-Lys-Tyr-Pro | - |
? |