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Literature summary extracted from

  • Baramova, E.N.; Shannon, J.D.; Bjarnason, J.B.; Gonias, S.L.; Fox, J.W.
    Interaction of hemorrhagic metalloproteinases with human alpha 2-macroglobulin (1990), Biochemistry, 29, 1069-1074.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.1 alpha1-Macroglobulin
-
 Crotalus atrox

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.24.1 Proteins + H2O Crotalus atrox preferential cleavage: -Leu, -Ile, -Val, -Phe ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.1 Crotalus atrox
-
 Western diamondback rattlesnake, 4 metalloproteinases: Ht-a, Ht-c, Ht-d, Ht-e
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.1 alpha2-macroglobulin + H2O
-
 Crotalus atrox ?
-
 ?
3.4.24.1 Gelatin + H2O
-
 Crotalus atrox ?
-
 ?
3.4.24.1 Proteins + H2O preferential cleavage: -Leu, -Ile, -Val, -Phe Crotalus atrox ?
-
 ?
3.4.24.1 Type IV collagen + H2O
-
 Crotalus atrox ?
-
 ?