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Literature summary extracted from
- Cathepsin D from pig myometrium (1984), Biochem. J., 219, 899-904.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.23.5 | Kallikrein | - |
Sus scrofa | |
| 3.4.23.5 | pepstatin | strong | Sus scrofa |  |
| 3.4.23.5 | phenylmethanesulfonyl fluoride | slight | Sus scrofa | |
| 3.4.23.5 | phenylpyruvate | - |
Sus scrofa | |
| 3.4.23.5 | Soybean trypsin inhibitor | - |
Sus scrofa | |
| 3.4.23.5 | tosylphenylalanylchloromethane | - |
Sus scrofa | |
| 3.4.23.5 | Val-D-Leu-Pro-Phe-Phe-Val-D-Leu | - |
Sus scrofa | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.4.23.5 | 0.0064 | - |
hemoglobin | - |
Sus scrofa |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.4.23.5 | 35000 | - |
gel filtration, equilibrium sedimentation | Sus scrofa |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.23.5 | Sus scrofa | - |
pig | - |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 3.4.23.5 | side-chain modification | glycoprotein | Sus scrofa |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.23.5 | myometrium | - |
Sus scrofa | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.23.5 | actomyosin + H2O | - |
Sus scrofa | ? | - |
? | |
| 3.4.23.5 | Albumin + H2O | bovine serum albumin | Sus scrofa | ? | - |
? | |
| 3.4.23.5 | casein + H2O | - |
Sus scrofa | ? | - |
? | |
| 3.4.23.5 | Hemoglobin + H2O | - |
Sus scrofa | ? | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.4.23.5 | ? | one main band of 31000 Da and two minor bands of 15000 Da and 43000 Da, SDS-PAGE | Sus scrofa |
Temperature Stability [°C]
| EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.4.23.5 | 40 | - |
pH 3, stable below | Sus scrofa |
| 3.4.23.5 | 50 | - |
pH 6, stable up to | Sus scrofa |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.23.5 | 3 | 3.3 | hemoglobin | Sus scrofa |
pH Stability
| EC Number | pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.23.5 | 3.5 | 6.5 | stable | Sus scrofa |
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