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Literature summary extracted from

  • Goldman-Levkovitz, S.; Rimon, A.; Rimon, S.
    Purification properties and specificity of cathepsin D from Cyprinus carpio (1995), Comp. Biochem. Physiol. B, 112, 147-151.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.23.5 pepstatin 0.001 mM, complete inhibition Cyprinus carpio

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.23.5 36000
-
 x * 36000, SDS-PAGE Cyprinus carpio

Organism

EC Number Organism UniProt Comment Textmining
3.4.23.5 Cyprinus carpio
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.23.5
-
 Cyprinus carpio

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.23.5 muscle
-
 Cyprinus carpio
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.23.5 additional information
-
-
 Cyprinus carpio

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.23.5 Albumin + H2O
-
 Cyprinus carpio ?
-
 ?
3.4.23.5 Hemoglobin + H2O
-
 Cyprinus carpio ?
-
 ?
3.4.23.5 insulin + H2O 56% cleavage at Tyr16-Leu17, 40% at Phe25-Tyr26. The minor points of cleavage are at Leu15-Tyr16, Phe24-Phe25, Gly23-Phe24, Leu11-Val12, Ala14-Leu15 and Gln4-His5 Cyprinus carpio ?
-
 ?
3.4.23.5 insulin + H2O beta-chain of oxidized insulin Cyprinus carpio ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.23.5 ? x * 36000, SDS-PAGE Cyprinus carpio

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.4.23.5 43 55
-
 Cyprinus carpio

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.4.23.5 20
-
 10 min, at pH 3.5 or at pH 7.5, stable Cyprinus carpio
3.4.23.5 43
-
 10 min, stable at pH 3.5, 40% loss of activity at pH 7.5 Cyprinus carpio
3.4.23.5 48.5
-
 10 min, stable at pH 3.5, 81% loss of activity at pH 7.5 Cyprinus carpio
3.4.23.5 54
-
 10 min, 13% loss of activity at pH 3.5, complete loss of activity at pH 7.5 Cyprinus carpio
3.4.23.5 60
-
 10 min, 35% loss of activity at pH 3.5, complete loss of activity at pH 7.5 Cyprinus carpio
3.4.23.5 66
-
 10 min, complete loss of activity at pH 3.5 and at pH 7.5 Cyprinus carpio

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.23.5 2.7 3.7 hemoglobin Cyprinus carpio
3.4.23.5 3
-
 albumin Cyprinus carpio

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.4.23.5 2 5 pH 2.0: about 55% of maximal activity, pH 5.0: about40% of maximal activity, with albumin as substrate Cyprinus carpio
3.4.23.5 2 4.5 pH 2.0: about 35% of maximal activity, pH 4.5: about 45% of maximal activity, hemoglobin as substrate Cyprinus carpio