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Literature summary extracted from
- Purification of pepsins and cathepsin D by affinity chromatography on Sepharose 4B with an immobilized synthetic inhibitor (1984), Anal. Biochem., 139, 265-271.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.23.1 | Val-D-Leu-Pro-Phe-Phe-Val-D-Leu | - |
Gallus gallus |  |
| 3.4.23.1 | Val-D-Leu-Pro-Phe-Phe-Val-D-Leu | - |
Homo sapiens | |
| 3.4.23.1 | Val-D-Leu-Pro-Phe-Phe-Val-D-Leu | - |
Sus scrofa | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.23.1 | Gallus gallus | - |
- |
- |
| 3.4.23.1 | Homo sapiens | - |
- |
- |
| 3.4.23.1 | Sus scrofa | - |
- |
- |
| 3.4.23.5 | Bos taurus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.23.1 | - |
Gallus gallus |
| 3.4.23.1 | - |
Homo sapiens |
| 3.4.23.1 | - |
Sus scrofa |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.23.5 | spleen | - |
Bos taurus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.4.23.5 | additional information | - |
affinity chromatography with the immobilized synthetic inhibitor Val-D-Leu-Pro-Phe-Phe-Val-D-Leu | Bos taurus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.23.5 | Glu-His-(4-nitro)Phe-Phe-Ala-Leu-NH2 + H2O | - |
Bos taurus | ? | - |
? | |
| 3.4.23.5 | Hemoglobin + H2O | - |
Bos taurus | ? | - |
? | |
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Release 2023.1 (January 2023)
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