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Literature summary extracted from

  • Wilson, L.R.; Good, R.T.; Panaccio, M.; Wijffels, G.L.; Sandeman, R.M.; Spithill, T.W.
    Fasciola hepatica: characterization and cloning of the major cathepsin B protease secreted by newly excysted juvenile liver fluke (1998), Exp. Parasitol., 88, 85-94.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.22.1
-
Fasciola hepatica

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.22.1 L-3-carboxy-2,3-trans-epoxypropionyl-leucylamido-(4-guanidino)butane E-64 Fasciola hepatica

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.22.1 extracellular
-
Fasciola hepatica
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.22.1 28790
-
derived from cDNA sequence Fasciola hepatica

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.22.1 Proteins + H2O Fasciola hepatica
-
?
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.1 Fasciola hepatica
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.22.1 benzyloxycarbonyl-Arg-4-methylcoumarin 7-amide + H2O
-
Fasciola hepatica benzyloxycarbonyl-Arg + 7-amino-4-methylcoumarin
-
?
3.4.22.1 benzyloxycarbonyl-Arg-Arg-4-methylcoumarin 7-amide + H2O
-
Fasciola hepatica benzyloxycarbonyl-Arg-Arg + 7-amino-4-methylcoumarin
-
?
3.4.22.1 benzyloxycarbonyl-Phe-Arg-4-methylcoumarin-7-amide
-
Fasciola hepatica benzyloxycarbonyl-Phe-Arg + 7-amino-4-methylcoumarin
-
?
3.4.22.1 Bovine serum albumin + H2O
-
Fasciola hepatica Hydrolyzed bovine serum albumin
-
?
3.4.22.1 Proteins + H2O
-
Fasciola hepatica ?
-
?
3.4.22.1 sheep immunoglobulin heavy chain + H2O
-
Fasciola hepatica hydrolyzed sheep immunoglobulin heavy chain
-
?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.22.1 7.5
-
-
Fasciola hepatica