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Literature summary extracted from
- Purification and properties of human acrosin (1973), Eur. J. Biochem., 39, 85-92.
General Stability
| EC Number | General Stability | Organism |
|---|---|---|
| 3.4.21.10 | lyophilization, unstable | Homo sapiens |
| 3.4.21.10 | ultrafiltration, unstable | Homo sapiens |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.21.10 | diisopropylfluorophosphate | - |
Homo sapiens |  |
| 3.4.21.10 | Nalpha-tosyl-L-lysine chloromethyl ketone | - |
Homo sapiens | |
| 3.4.21.10 | ovomucoid | chicken | Homo sapiens | |
| 3.4.21.10 | Trypsin inhibitor | bovine pancreatic; lima-bean; soybean | Homo sapiens |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.4.21.10 | additional information | - |
additional information | - |
Homo sapiens |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.4.21.10 | 76000 | - |
gel filtration | Homo sapiens |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.10 | additional information | Homo sapiens | digestion of zona pellucida by sperm, glycoprotein layer surrounding the oocyte | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.21.10 | Homo sapiens | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.21.10 | - |
Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.21.10 | semen | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.4.21.10 | additional information | - |
- |
Homo sapiens |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 3.4.21.10 | 4°C, pH 3.2, 0.5 M KCl, stable for weeks | Homo sapiens |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.10 | additional information | digestion of zona pellucida by sperm, glycoprotein layer surrounding the oocyte | Homo sapiens | ? | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.4.21.10 | monomer | 1 * 76000, SDS-PAGE | Homo sapiens |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.21.10 | 8.2 | - |
- |
Homo sapiens |
pH Range
| EC Number | pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.21.10 | 6 | 10.5 | pH 6.0: about 20% of maximal activity, pH 10.5: about 25% of maximal activity | Homo sapiens |
pH Stability
| EC Number | pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.21.10 | 4 | - |
4°C, partially purified enzyme, stable | Homo sapiens |
| 3.4.21.10 | 8.1 | - |
4°C, 60% loss of activity after 2 min | Homo sapiens |
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Release 2023.1 (January 2023)
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