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Literature summary extracted from
- Studies on ram acrosin. Activation of proacrosin accompanying the isolation of acrosin from spermatozoa, and purification of the enzyme by affinity chromatography (1978), Biochem. J., 175, 227-238.
General Stability
| EC Number | General Stability | Organism |
|---|---|---|
| 3.4.21.10 | Ca2+ stabilizes | Ovis aries |
| 3.4.21.10 | freeze-drying: beta-acrosin: very stable | Ovis aries |
| 3.4.21.10 | more, psi-acrosin: unstable | Ovis aries |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.21.10 | 4-(4'-aminophenoxypropoxy)benzamidine | - |
Ovis aries |  |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.4.21.10 | membrane | bound | Ovis aries | 16020 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.21.10 | Ca2+ | activates | Ovis aries | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.4.21.10 | 38000 | - |
x * 38000, SDS-PAGE, beta-acrosin | Ovis aries |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.10 | additional information | Ovis aries | digestion of zona pellucida by sperm, glycoprotein layer surrounding the oocyte | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.21.10 | Ovis aries | - |
beta-acrosin, psi-acrosin | - |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 3.4.21.10 | side-chain modification | glycoprotein | Ovis aries |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.21.10 | semen | - |
Ovis aries | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.10 | additional information | digestion of zona pellucida by sperm, glycoprotein layer surrounding the oocyte | Ovis aries | ? | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.4.21.10 | ? | x * 38000, SDS-PAGE, beta-acrosin | Ovis aries |
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Release 2023.1 (January 2023)
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