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Literature summary extracted from

  • Barabe, J.; Huberdeau, D.
    A micromethod for the determination of the activities of kininases in rat plasma. Kinetics and inhibitory characteristics (1991), Biochem. Pharmacol., 41, 821-827.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.17.3 1,10-phenanthroline
-
 Rattus norvegicus
3.4.17.3 2-mercaptomethyl-3-guanidinoethylthiopropanoic acid
-
 Rattus norvegicus
3.4.17.3 EDTA
-
 Rattus norvegicus
3.4.17.3 phosphormaidon
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.17.3 6.93
-
 hippuryl-L-Arg
-
 Rattus norvegicus
3.4.17.3 35.8
-
 Hippuryl-L-Lys
-
 Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.4.17.3 Rattus norvegicus
-
 enzyme form CN1 and CN2
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.17.3 plasma
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.17.3 Hippuryl-L-Arg + H2O
-
 Rattus norvegicus Hippuric acid + L-Arg
-
 ?
3.4.17.3 hippuryl-L-His-L-Leu + H2O
-
 Rattus norvegicus hippuryl-L-His + L-Leu
-
 ?
3.4.17.3 Hippuryl-L-Lys + H2O
-
 Rattus norvegicus Hippuric acid + L-Lys
-
 ?
3.4.17.3 hippuryl-L-Lys-L-Leu + H2O
-
 Rattus norvegicus hippuryl-L-Lys + L-Leu
-
 ?