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Literature summary extracted from
- Carboxypeptidase A (1984), Methods Enzym. Anal. , 3rd Ed. (Bergmeyer, H. U. , ed. ), 5, 44-55.
No PubMed abstract available
Crystallization (Commentary)
| EC Number | Crystallization (Comment) | Organism |
|---|---|---|
| 3.4.17.1 | - |
Bos taurus |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.17.1 | 2-benzyl-3-mecaptopropionate | Ki: 11 nM | Bos taurus |  |
| 3.4.17.1 | Benzylsuccinic acid | Ki: 450 nM | Bos taurus | |
| 3.4.17.1 | Benzylsuccinic acid | - |
Homo sapiens | |
| 3.4.17.1 | mercaptoacetyl-D-Phe | Ki: 220 nM | Bos taurus | |
| 3.4.17.1 | N-phenylphosphoryl-L-phenylalanine | Ki: 0.0021 mM | Bos taurus | |
| 3.4.17.1 | Phe phosphonate | Ki: 0.001 mM | Bos taurus | |
| 3.4.17.1 | polypeptide inhibitor | molecular weight 10000, Ki: 1 nM | Bos taurus |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.4.17.1 | 0.1 | - |
N-(2-furanacryloyl)-Phe-Phe | - |
Bos taurus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.17.1 | Bos taurus | - |
- |
- |
| 3.4.17.1 | Homo sapiens | - |
- |
- |
Renatured (Commentary)
| EC Number | Renatured (Comment) | Organism |
|---|---|---|
| 3.4.17.1 | reversible denaturation: up to at least 7 M urea, irreversible: 33% ethanol-water mixture | Bos taurus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.17.1 | N-(2-furanacryloyl)-Phe-Phe + H2O | - |
Bos taurus | N-(2-furanacryloyl)-Phe + Phe | - |
ir | |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.4.17.1 | 25 | - |
assay at | Bos taurus |
Turnover Number [1/s]
| EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.4.17.1 | 667 | - |
N-(2-furanacryloyl)-Phe-Phe | - |
Bos taurus | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.17.1 | 7.5 | - |
assay at | Homo sapiens |
| 3.4.17.1 | 7.5 | - |
assay at | Bos taurus |
Ki Value [mM]
| EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.4.17.1 | 0.000001 | - |
polypeptide inhibitor | molecular weight 10000 | Bos taurus | |
| 3.4.17.1 | 0.000011 | - |
2-benzyl-3-mecaptopropionate | - |
Bos taurus | |
| 3.4.17.1 | 0.00022 | - |
mercaptoacetyl-D-Phe | - |
Bos taurus | |
| 3.4.17.1 | 0.001 | - |
Phe phosphonate | - |
Bos taurus | |
| 3.4.17.1 | 0.0021 | - |
N-phenylphosphoryl-L-phenylalanine | - |
Bos taurus | |
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