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Literature summary extracted from

  • McDonald, J.K.; Callahan, P.X.; Ellis, S.
    Preparation and specificity of dipeptidyl aminopeptidase I (1972), Methods Enzymol., 25B, 272-281.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
3.4.14.1 Bos taurus
-
-
-
3.4.14.1 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.14.1
-
Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.14.1 hypophysis
-
Bos taurus
-
3.4.14.1 liver
-
Rattus norvegicus
-
3.4.14.1 spleen
-
Rattus norvegicus
-
3.4.14.1 spleen
-
Bos taurus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.14.1 18.6
-
-
Bos taurus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.14.1 Ala-Ala-2-naphthylamide + H2O
-
Bos taurus Ala-Ala + 2-naphthylamine
-
?
3.4.14.1 Ala-Arg-2-naphthylamide + H2O
-
Bos taurus Ala-Arg + 2-naphthylamine
-
?
3.4.14.1 beta-corticotropin + H2O succesive removal of dipeptides from the NH2 terminus Rattus norvegicus Ser-Tyr + Ser-Met + Glu-His + Phe-Arg + Trp-Gly
-
?
3.4.14.1 beta-corticotropin + H2O succesive removal of dipeptides from the NH2 terminus Bos taurus Ser-Tyr + Ser-Met + Glu-His + Phe-Arg + Trp-Gly
-
?
3.4.14.1 Glu-His-2-naphthylamide + H2O
-
Bos taurus Glu-His + 2-naphthylamine
-
?
3.4.14.1 Gly-Arg-2-naphthylamide + H2O
-
Rattus norvegicus Gly-Arg + 2-naphthylamine
-
?
3.4.14.1 Gly-Phe-2-naphthylamide + H2O
-
Bos taurus Gly-Phe + 2-naphthylamine
-
?
3.4.14.1 Gly-Trp-2-naphthylamide + H2O
-
Bos taurus Gly-Trp + 2-naphthylamine
-
?
3.4.14.1 additional information inability to remove dipeptides with an N-terminal Arg or Lys, and inability to cleave the bond on either side of Pro Rattus norvegicus ?
-
?
3.4.14.1 additional information inability to remove dipeptides with an N-terminal Arg or Lys, and inability to cleave the bond on either side of Pro Bos taurus ?
-
?
3.4.14.1 Phe-Arg-2-naphthylamide + H2O
-
Bos taurus Phe-Arg + 2-naphthylamine
-
?
3.4.14.1 Pro-Arg-2-naphthylamide + H2O
-
Bos taurus Pro-Arg + 2-naphthylamine
-
?
3.4.14.1 Ser-Met-2-naphthylamide + H2O
-
Bos taurus Ser-Met + 2-naphthylamine
-
?
3.4.14.1 Ser-Tyr-2-naphthylamide + H2O
-
Bos taurus Ser-Tyr + 2-naphthylamine
-
?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.14.1 4
-
-
Bos taurus