Any feedback?
Literature summary extracted from
- Purification and characterization of guinea pig serum aminoacylproline hydrolase (aminopeptidase P) (1992), Biochim. Biophys. Acta, 1119, 140-147.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.11.9 | 1,10-phenanthroline | - |
Cavia porcellus |  |
| 3.4.11.9 | 2-mercaptoethanol | - |
Cavia porcellus | |
| 3.4.11.9 | 2-mercaptomethyl-3-guanidinoethylthiopropanoic acid | - |
Cavia porcellus | |
| 3.4.11.9 | 4-hydroxymercuribenzoate | partial | Cavia porcellus | |
| 3.4.11.9 | bradykinin | - |
Cavia porcellus | |
| 3.4.11.9 | captopril | - |
Cavia porcellus | |
| 3.4.11.9 | Cu2+ | - |
Cavia porcellus | |
| 3.4.11.9 | EDTA | - |
Cavia porcellus | |
| 3.4.11.9 | Hg2+ | - |
Cavia porcellus | |
| 3.4.11.9 | Mn2+ | 0.01 M | Cavia porcellus | |
| 3.4.11.9 | Ni2+ | - |
Cavia porcellus | |
| 3.4.11.9 | Pb2+ | - |
Cavia porcellus | |
| 3.4.11.9 | phenylmethylsulfonyl fluoride | - |
Cavia porcellus | |
| 3.4.11.9 | phosphoramidon | - |
Cavia porcellus | |
| 3.4.11.9 | Zn2+ | - |
Cavia porcellus | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.4.11.9 | 0.0007 | - |
Arg-Pro-Pro-benzylamide | - |
Cavia porcellus | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.11.9 | Ca2+ | 0.5-1.0 mM, slight activation | Cavia porcellus | |
| 3.4.11.9 | Co2+ | 0.03 mM, activates | Cavia porcellus | |
| 3.4.11.9 | Mg2+ | 1 mM, activates | Cavia porcellus | |
| 3.4.11.9 | Mn2+ | 0.25-1 mM activates | Cavia porcellus | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.4.11.9 | 81500 | - |
x * 81500 + x * 89000, SDS-PAGE | Cavia porcellus |
| 3.4.11.9 | 89000 | - |
x * 81500 + x * 89000, SDS-PAGE | Cavia porcellus |
| 3.4.11.9 | 217000 | - |
gel filtration | Cavia porcellus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.11.9 | Cavia porcellus | - |
- |
- |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 3.4.11.9 | side-chain modification | glycoprotein | Cavia porcellus |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.11.9 | - |
Cavia porcellus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.4.11.9 | additional information | - |
- |
Cavia porcellus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.11.9 | Arg-Pro-Pro-benzylamide + H2O | - |
Cavia porcellus | Arg + Pro-Pro-benzylamide | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.4.11.9 | ? | x * 81500 + x * 89000, SDS-PAGE | Cavia porcellus |
Turnover Number [1/s]
| EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.4.11.9 | 125 | - |
Arg-Pro-Pro-benzylamide | - |
Cavia porcellus | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
