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Literature summary extracted from

  • Lalu, K.; Lampelo, S.; Nummelin-Kortelainen, M.; Vanha-Perttula, T.
    Purification and partial characterization of aminopeptidase A from the serum of pregnant and non-pregnant women (1984), Biochim. Biophys. Acta, 789, 324-333.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.11.7 Sodium azide
-
 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.11.7 0.091 1.2 Glu-beta-naphthylamide value depending on source of enzyme and presence of divalent cations Homo sapiens
3.4.11.7 0.72 0.846 Asp-beta-naphthylamide maternal and normal serum Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.11.7 Ba2+ activation Homo sapiens
3.4.11.7 Ca2+ activation Homo sapiens
3.4.11.7 Sr2+ activation Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.11.7 260000
-
 gel filtration Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.7 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.11.7
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.11.7 serum maternal and non-maternal Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.11.7 additional information
-
-
 Homo sapiens

Storage Stability

EC Number Storage Stability Organism
3.4.11.7 4°C, or room temperature, or -18°C, without Ba2+ Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.11.7 Asp-beta-naphthylamide + H2O
-
 Homo sapiens Asp + naphthylamine
-
 ?
3.4.11.7 Glu-beta-naphthylamide + H2O
-
 Homo sapiens Glu + naphthylamine
-
 ?
3.4.11.7 additional information slow hydrolysis of Ala-beta-naphthylamide, Arg-beta-naphthylamide Homo sapiens ?
-
 ?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.4.11.7 65
-
 41-45% activity Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.11.7 6.75 7.25 activity in Tris-HCl buffer higher than in phosphate buffer Homo sapiens