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Literature summary extracted from

  • Hiraoka, B.Y.; Fukasawa, K.; Harada, M.
    Purification and characterization of two novel arginine aminopeptidases from Streptococcus mitis ATCC 9811 (1983), J. Biochem., 94, 1201-1208.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.4.11.6 dithiothreitol activation, enzyme II Streptococcus mitis
3.4.11.6 EDTA activation Streptococcus mitis
3.4.11.6 sulfhydryl compounds activation, enzyme I Streptococcus mitis

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.11.6 2-mercaptoethanol enzyme II Streptococcus mitis
3.4.11.6 Cd2+
-
 Streptococcus mitis
3.4.11.6 Co2+
-
 Streptococcus mitis
3.4.11.6 Cu2+
-
 Streptococcus mitis
3.4.11.6 cysteine enzyme II Streptococcus mitis
3.4.11.6 Hg2+
-
 Streptococcus mitis
3.4.11.6 p-chloromercuribenzoate
-
 Streptococcus mitis
3.4.11.6 Pb2+
-
 Streptococcus mitis

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.11.6 0.0026
-
 L-Arg-beta-naphthylamide enzyme I Streptococcus mitis
3.4.11.6 0.038
-
 L-Arg-beta-naphthylamide enzyme II Streptococcus mitis

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.11.6 52000 58000 gel filtration, enzyme I Streptococcus mitis
3.4.11.6 360000
-
 gel filtration, enzyme II Streptococcus mitis

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.6 Streptococcus mitis
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.11.6 2 forms Streptococcus mitis

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.11.6 additional information
-
-
 Streptococcus mitis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.11.6 Arg-Gly-Tyr-Ala-Leu-Gly + H2O
-
 Streptococcus mitis Arg + Gly-Tyr-Ala-Leu-Gly
-
 ?
3.4.11.6 Arg-Tyr-Leu-Pro-Thr + H2O proctolin Streptococcus mitis Arg + Tyr-Leu-Pro-Thr
-
 ?
3.4.11.6 Arg-Val-Tyr-Ile-His-Pro-Phe + H2O angiotensin III Streptococcus mitis Arg + Val-Tyr-Ile-His-Pro-Phe
-
 ?
3.4.11.6 L-Arg-2-naphthylamide + H2O
-
 Streptococcus mitis L-Arg + 2-naphthylamine
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.11.6 monomer 1 * ?, enzyme I, SDS-PAGE Streptococcus mitis