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Literature summary extracted from

  • Mäkinen, K.K.
    The proline iminopeptidases of human oral cavity (1969), Acta Chem. Scand., 23, 1409-1438.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.11.5 diphenylcarbamoyl chloride enzymes II and III oral microorganisms
3.4.11.5 L-Hydroxyprolyl-2-naphthylamide competitive oral microorganisms
3.4.11.5 N-ethylmaleimide
-
 oral microorganisms
3.4.11.5 p-chloromercuribenzoate
-
 oral microorganisms

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.11.5 additional information
-
 additional information dependency of Km on pH oral microorganisms

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.11.5 additional information no metalloenzyme oral microorganisms

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.5 oral microorganisms
-
 enzyme secreted into saliva
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.11.5 3 enzymes, II and III specific for naphthylamides of L-Pro and L-Hyp oral microorganisms

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.11.5 saliva
-
 oral microorganisms
-

Storage Stability

EC Number Storage Stability Organism
3.4.11.5 4°C, 8 weeks oral microorganisms

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.11.5 L-hydroxyproline-2-naphthylamide + H2O enzymes II and III oral microorganisms L-hydroxyproline + 2-naphthylamine
-
 ?
3.4.11.5 L-prolyl-peptide + H2O influence of amino acid adjacent to N-terminal L-Pro on rate of hydrolysis oral microorganisms L-proline + peptide
-
 ?
3.4.11.5 N-L-Pro-2-naphthylamide + H2O enzymes II and III specific for oral microorganisms L-proline + naphthylamine
-
 ?

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.4.11.5 6.5 8.5
-
 oral microorganisms