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Literature summary extracted from

  • Maekinen, K.K.; Syed, S.A.; Maekinen, P.L.; Loesche, W.J.
    Dominance of inminopeptidase activity in the human oral bacterium Treponema denticola ATCC 35405 (1987), Curr. Microbiol., 14, 341-346.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.4.11.5 dithiothreitol restores activity after deactivation with p-chloromercuribenzoate Treponema denticola

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.11.5 1-(Ethoxycarbonyl)-2-ethoxy-1,2-dihydroquinone
-
Treponema denticola
3.4.11.5 Diazotized sulfanilic acid
-
Treponema denticola
3.4.11.5 diethyldicarbonate
-
Treponema denticola
3.4.11.5 p-chloromercuribenzoate
-
Treponema denticola
3.4.11.5 Phenylmethylsulfonylfluoride
-
Treponema denticola
3.4.11.5 Tetranitromethane
-
Treponema denticola

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.11.5 cytosol
-
Treponema denticola 5829
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.11.5 100000
-
? * 100000, SDS-PAGE Treponema denticola

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.5 Treponema denticola
-
ATCC 35405
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.11.5 partial, 3 enzymes: I, II, III Treponema denticola

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.11.5 additional information
-
-
Treponema denticola
3.4.11.5 0.48
-
type III Treponema denticola

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.11.5 N-L-Pro-2-naphthylamide + H2O
-
Treponema denticola L-proline + naphthylamine
-
?

Subunits

EC Number Subunits Comment Organism
3.4.11.5 More ? * 100000, SDS-PAGE Treponema denticola

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.11.5 7 7.5 enzyme III Treponema denticola
3.4.11.5 7 8 enzyme I and II, activity in Tris-buffer higher than in phosphate buffer Treponema denticola

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.4.11.5 5
-
no activity below Treponema denticola