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Literature summary extracted from

  • Chenoweth, D.; Mitchel, R.E.J.; Smith, E.L.
    Aminotripeptidase of swine kidney. I. Isolation and characterization of three different forms; utility of the enzyme in sequence work (1973), J. Biol. Chem., 248, 1672-1683.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.11.4 1,10-phenanthroline
-
Sus scrofa
3.4.11.4 5,5'-dithiobis(2-nitrobenzoate)
-
Sus scrofa
3.4.11.4 Carboxy-o-phenanthroline
-
Sus scrofa
3.4.11.4 N-ethylmaleimide
-
Sus scrofa
3.4.11.4 p-hydroxymercuribenzoate
-
Sus scrofa
3.4.11.4 Zn2+
-
Sus scrofa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.11.4 20
-
Gly-Gly-Gly
-
Sus scrofa

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.11.4 Zn2+ 0.5 mol per subunit Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.4 Sus scrofa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.11.4 3 forms Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.11.4 kidney
-
Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.11.4 Gly-Gly-Gly + H2O
-
Sus scrofa Gly + Gly-Gly
-
?
3.4.11.4 Leu-Gly-Gly + H2O Tyr Sus scrofa Leu + Gly-Gly
-
?
3.4.11.4 Leu-Gly-Gly + H2O Leu can be replaced by Ala, Phe, Gly-Pro Sus scrofa Leu + Gly-Gly
-
?
3.4.11.4 Leu-Gly-Gly + H2O Hyp, Thr, His Sus scrofa Leu + Gly-Gly
-
?
3.4.11.4 additional information
-
Sus scrofa ?
-
?

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3.4.11.4 2030
-
Gly-Gly-Gly
-
Sus scrofa

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.11.4 7.8 8
-
Sus scrofa

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.4.11.4 9
-
no activity above Sus scrofa