Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Balliano, G.; Milla, P.; Ceruti, M.; Viola, F.; Carrano, L.; Cattel, L.
    Differential inhibition of fungal oxidosqualene cyclase by 6E and 6Z isomers of 2,3-epoxy-10-aza-10,11-dihydrosqualene (1993), FEBS Lett., 320, 203-206.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.4.99.7 2,3-Epoxy-10-aza-10,11-dehydrosqualene 6E isomer strongly inhibits enzyme in both cell cultures and microsomes; weak inhibition by 6Z isomer Candida albicans
5.4.99.7 2,3-Epoxy-10-aza-10,11-dehydrosqualene 6E isomer strongly inhibits enzyme in both cell cultures and microsomes; 6Z isomer has no effect on microsomal enzyme Saccharomyces cerevisiae

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
5.4.99.7 microsome
-
 Saccharomyces cerevisiae
-
-
5.4.99.7 microsome
-
 Candida albicans
-
-

Organism

EC Number Organism UniProt Comment Textmining
5.4.99.7 Candida albicans
-
-
-
5.4.99.7 Saccharomyces cerevisiae
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.4.99.7 cell culture
-
 Saccharomyces cerevisiae
-
5.4.99.7 cell culture
-
 Candida albicans
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.4.99.7 (S)-squalene-2,3-epoxide
-
 Saccharomyces cerevisiae Lanosterol
-
 ?
5.4.99.7 (S)-squalene-2,3-epoxide
-
 Candida albicans Lanosterol
-
 ?