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Literature summary extracted from

  • Lampelo, S.; Vanha-Perttula, T.
    Fractionation and characterization of cystine aminopeptidase (oxytocinase) and arylamidase of the human placenta (1979), J. Reprod. Fertil., 56, 285-296.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.11.3 1,10-phenanthroline
-
 Homo sapiens
3.4.11.3 2,2'-dipyridyl
-
 Homo sapiens
3.4.11.3 Co2+ reverses EDTA inhibition Homo sapiens
3.4.11.3 EDTA form I inhibited, form II uninfluenced or slightly activated Homo sapiens
3.4.11.3 EGTA
-
 Homo sapiens
3.4.11.3 L-methionine form I inhibited, form II slightly activated Homo sapiens
3.4.11.3 Ni2+
-
 Homo sapiens
3.4.11.3 Zn2+ at high concentration Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.11.3 lysosome
-
 Homo sapiens 5764
-
3.4.11.3 microsome
-
 Homo sapiens
-
-
3.4.11.3 mitochondrion
-
 Homo sapiens 5739
-
3.4.11.3 nucleus low activity Homo sapiens 5634
-
3.4.11.3 soluble
-
 Homo sapiens
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.11.3 Co2+ reverses EDTA inhibition Homo sapiens
3.4.11.3 Zn2+ reverses EDTA inhibition Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.11.3 76400
-
 enzyme II, gel filtration Homo sapiens
3.4.11.3 309000
-
 enzyme I, gel filtration Homo sapiens
3.4.11.3 340000
-
 gel filtration Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.3 Homo sapiens
-
 2 forms: I, II
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.11.3 placenta
-
 Homo sapiens
-

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.4.11.3 37
-
 assay at Homo sapiens

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.4.11.3 55
-
 15 min, form I: about 20% loss, form II: about 70% loss of activity Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.11.3 6
-
 form II Homo sapiens
3.4.11.3 6.5
-
 form II Homo sapiens