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Literature summary extracted from
- A soluble 2,3-oxidosqualene sterol cyclase (1967), J. Biol. Chem., 242, 3014-3015.
General Stability
| EC Number | General Stability | Organism |
|---|---|---|
| 5.4.99.7 | rapid loss of activity on freezing and thawing | Sus scrofa |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.4.99.7 | 2,2-dimethyl-3-[(3E,7E,11E,15E)-3,7,12,16,20-pentamethylhenicosa-3,7,11,15,19-pentaen-1-yl]aziridine | - |
Sus scrofa |  |
| 5.4.99.7 | NEM | 1 mM, 20% inhibition | Sus scrofa | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 5.4.99.7 | microsome | - |
Sus scrofa | - |
- |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.4.99.7 | Sus scrofa | - |
hog | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 5.4.99.7 | - |
Sus scrofa |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 5.4.99.7 | liver | - |
Sus scrofa | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 5.4.99.7 | additional information | - |
- |
Sus scrofa |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 5.4.99.7 | 0°C, stable | Sus scrofa |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.4.99.7 | (S)-squalene-2,3-epoxide | - |
Sus scrofa | Lanosterol | - |
? | |
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Release 2023.1 (January 2023)
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