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Literature summary extracted from

  • Schalk, C.; d'Orchymont, H.; Jauch, M.F.; Tarnus, C.
    3-Amino-2-tetralone derivatives: novel potent and selective inhibitors of aminopeptidase-M (EC 3.4.11.2) (1994), Arch. Biochem. Biophys., 311, 42-46.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.11.2 3-amino-2-tetralone derivatives Ki: 0.000020 - 0.03 mM, not inhibitory or poor inhibitors to EC 3.4.11.7, EC 3.4.11.6, EC 3.4.11.1 Sus scrofa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.11.2 0.5
-
Leu-p-nitroanilide
-
Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.11.2 aminoacyl peptide Sus scrofa
-
?
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.2 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.11.2 kidney
-
Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.11.2 aminoacyl peptide
-
Sus scrofa ?
-
?
3.4.11.2 Leu-p-nitroanilide + H2O
-
Sus scrofa Leu + p-nitroaniline
-
?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.4.11.2 0.00002 0.03 3-amino-2-tetralone derivatives not inhibitory or poor inhibitors to EC 3.4.11.7, EC 3.4.11.6, EC 3.4.11.1 Sus scrofa