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Literature summary extracted from
- Isolation and functional characterization of mutant ferrochelatases in Saccharomyces cerevisiae (1996), Biochimie, 78, 144-152.
Protein Variants
| EC Number | Protein Variants | Comment | Organism |
|---|---|---|---|
| 4.98.1.1 | G47S | thermosensitive phenotype | Saccharomyces cerevisiae |
| 4.98.1.1 | L62F | increase of Vmax and Km | Saccharomyces cerevisiae |
| 4.98.1.1 | S102F | thermosensitive phenotype | Saccharomyces cerevisiae |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 4.98.1.1 | mitochondrion | inner membrane | Saccharomyces cerevisiae | 5739 | - |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.98.1.1 | protoporphyrin IX + Fe2+ | Saccharomyces cerevisiae | final step of heme biosynthesis | ? | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.98.1.1 | Saccharomyces cerevisiae | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.98.1.1 | protoporphyrin + Fe2+ | - |
Saccharomyces cerevisiae | protoheme + 2 H+ | - |
? | |
| 4.98.1.1 | protoporphyrin IX + Fe2+ | final step of heme biosynthesis | Saccharomyces cerevisiae | ? | - |
? | |
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Release 2023.1 (January 2023)
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