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Literature summary extracted from

  • DeBose-Boyd, R.A.; Nyame, A.K.; Cummings, R.D.
    Schistosoma mansoni: characterization of an alpha 1-3 fucosyltransferase in adult parasites (1996), Exp. Parasitol., 82, 1-10.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.152 N-ethylmaleimide 14 mM causes 50% inhibition Schistosoma mansoni

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.152 0.3
-
lacto-N-neotetraose
-
Schistosoma mansoni

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.152 Mn2+
-
Schistosoma mansoni

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.152 Schistosoma mansoni
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.152 GDP-fucose + Galbeta1-4GlcNAc-R
-
Schistosoma mansoni GDP + Galbeta1-4(Fucalpha1-3)GlcNAc-R Lewis x determinant ?
2.4.1.152 GDP-fucose + lacto-N-neotetraose
-
Schistosoma mansoni GDP + lacto-N-fucopentaose III
-
?
2.4.1.152 GDP-fucose + NeuAcalpha2-3Galbeta1-4GlcNAc rate of reaction below 5% of the rate obtained toward nonsialylated acceptor Schistosoma mansoni GDP + NeuAcalpha2-3Galbeta1-4(Fucalpha1-3)GlcNAc sialyl Lewis x ?
2.4.1.152 additional information the enzyme does not transfer efficiently to the isomeric oligosaccharide lacto-N-tetraose Schistosoma mansoni ?
-
?
2.4.1.152 additional information the enzyme has acceptor specificity properties similar to that of the human myeloid enzyme FTIV Schistosoma mansoni ?
-
?