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Literature summary extracted from
- Different characteristics of ferrochelatase in cultured fibroblasts of erythropoietic protoporphyria patients and normal controls (1990), Biochim. Biophys. Acta, 1039, 339-342.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.98.1.1 | iodacetic acid | - |
Homo sapiens |  |
| 4.98.1.1 | N-ethylmaleimide | - |
Homo sapiens | |
| 4.98.1.1 | p-chloromercuribenzoate | - |
Homo sapiens | |
| 4.98.1.1 | Pb2+ | - |
Homo sapiens | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.98.1.1 | protoporphyrin IX + Fe2+ | Homo sapiens | final step of heme biosynthesis | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.98.1.1 | Homo sapiens | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 4.98.1.1 | fibroblast | cultured | Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.98.1.1 | protoporphyrin + Fe2+ | - |
Homo sapiens | protoheme + 2 H+ | - |
? | |
| 4.98.1.1 | protoporphyrin IX + Fe2+ | final step of heme biosynthesis | Homo sapiens | ? | - |
? | |
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