Literature summary extracted from

Hagen, W.R.; Vanoni, M.A.; Rosenbaum, K.; Schnackerz, K.D.
On the iron-sulfur clusters in the complex redox enzyme dihydropyrimidine dehydrogenase (2000), Eur. J. Biochem., 267, 3640-3646.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
1.3.1.2	Sulfide	-	Sus scrofa

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
1.3.1.2	Iron	2 * 2 [4Fe-4S] clusters close in space with 16 atoms of non-heme iron, structure	Sus scrofa

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.3.1.2	Sus scrofa	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.3.1.2	liver	-	Sus scrofa	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.3.1.2	5,6-dihydrouracil + NADP+	-	Sus scrofa	uracil + NADPH	-	r
1.3.1.2	uracil + NADPH	-	Sus scrofa	5,6-dihydrouracil + NADP+	-	r

Subunits

EC Number	Subunits	Comment	Organism
1.3.1.2	dimer	-	Sus scrofa

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.3.1.2	flavin	-	Sus scrofa
1.3.1.2	NADPH	-	Sus scrofa

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Release 2023.1 (January 2023)